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JUP 抗体

The 小鼠 单克隆 anti-JUP antibody is suitable to detect JUP in samples from 人, 小鼠, 大鼠, 小鸡, 犬, Cow 和 Cat. It has been validated for WB, IF, IHC, FACS 和 ELISA.
产品编号 ABIN6939839
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for JUP 抗体 (ABIN6939839)

抗原

See all JUP 抗体
JUP (Junction Plakoglobin (JUP))

适用

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人, 小鼠, 大鼠, 小鸡, 犬, Cow, Cat

宿主

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小鼠

克隆类型

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单克隆

标记

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This JUP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

克隆位点

15F11
  • 原理

    Catenin, gamma (Cardiomyocyte Marker) Antibody

    特异性

    It recognizes a protein of 80-87 kDa, identified as gamma-catenin. The catenins (°™, æ, Á and 79oΩL) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. °™ T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. °™ T-catenin binds to °™ E-catenin as well as to æ-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for °™-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant, full length chicken Catenin gamma protein

    亚型

    IgG1, kappa
  • 应用备注

    Positive Control: HeLa, SK-BR3, A431, HT20, 293, HepG2, A549 or MCF-7 cells. Skin.

    Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1.0 μg/mL)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    JUP (Junction Plakoglobin (JUP))

    别名

    JUP

    背景

    ARVD12, Catenin (cadherin-associated protein), gamma 80 kDa, Catenin gamma, CTNNG, Desmoplakin III, Desmoplakin-3, DP3, DPIII, Junction Plakoglobin, PDGB, PKGB

    HeLa, SK-BR3 or MCF-7 cells.

    分子量

    80-87kDa

    基因ID

    3728, 514174

    UniProt

    P14923

    途径

    Cell-Cell Junction Organization, Maintenance of Protein Location
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