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Integrin beta 3 抗体

Cited in 1 publication. The 小鼠 单克隆 anti-Integrin beta 3 antibody (Clone VI-PL2) (ABIN967485) specifically detects Integrin beta 3 in WB, FACS 和 IHC (fro). The antibody is reactive with 人, Cow, Baboon, Cynomolgus 和 猕猴 samples.
产品编号 ABIN967485
发货至: 中国
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Quick Overview for Integrin beta 3 抗体 (ABIN967485)

抗原

See all Integrin beta 3 (ITGB3) 抗体
Integrin beta 3 (ITGB3)

适用

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人, Cow, Baboon, Cynomolgus, 猕猴

宿主

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小鼠

克隆类型

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单克隆

标记

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This Integrin beta 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

VI-PL2
  • 产品特性

    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    亚型

    IgG1 kappa
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4° C.
  • Mason, André, Bensussan, Buckley, Civin, Clark, de Haas, Goyert, Hadam, Hart, Horejsí, Meuer, Morissey, Schwartz-Albiez, Shaw, Simmons, Uguccioni, van der Schoot, Viver, Zola: "CD antigens 2001." in: Tissue antigens, Vol. 58, Issue 6, pp. 425-30, (2002) (PubMed).

  • 抗原

    Integrin beta 3 (ITGB3)

    别名

    CD61

    背景

    Reacts with integrin beta3, a 105 kDa transmembrane glycoprotein, expressed on platelets, megakaryocytes, osteoclasts and endothelia. Integrin beta3 associates with gpIIa (CD41) to form the CD41/CD61 complex which mediates platelet adhesion and aggregation. CD61 also associates with CD51 to form the CD51/CD61 complex (vitronectin receptor). CD61 appears to bind to fibrinogen, fibronectin, vWF, vitronectin, and thrombospondin to mediate cell adhesion. This antibody is routinely tested by flow cytometric analysis.
    Synonyms: Integrin beta3 Chain

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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