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WIF1 抗体

This anti-WIF1 antibody is a 小鼠 单克隆 antibody detecting WIF1 in WB, IHC, ELISA 和 IF. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN967258
发货至: 中国

Quick Overview for WIF1 抗体 (ABIN967258)

抗原

See all WIF1 抗体
WIF1 (WNT Inhibitory Factor 1 (WIF1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This WIF1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

克隆位点

1G5
  • 纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human WIF1 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    Immunofluorescence: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Veeck, Wild, Fuchs, Schüffler, Hartmann, Knüchel, Dahl: "Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer." in: BMC cancer, Vol. 9, pp. 217, (2009) (PubMed).

    Kawakami, Hirata, Yamamura, Kikuno, Saini, Majid, Tanaka, Kawamoto, Enokida, Nakagawa, Dahiya: "Functional significance of Wnt inhibitory factor-1 gene in kidney cancer." in: Cancer research, Vol. 69, Issue 22, pp. 8603-10, (2009) (PubMed).

  • 抗原

    WIF1 (WNT Inhibitory Factor 1 (WIF1))

    别名

    WIF1

    背景

    The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers.
    Synonyms: WIF-1, WIF

    分子量

    42kDa

    基因ID

    11197

    途径

    WNT signaling, Positive Regulation of fat Cell Differentiation
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