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NAMPT 抗体

Cited in 2+ publications. The 单克隆 anti-NAMPT antibody (ABIN967254) specifically detects NAMPT in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN967254
发货至: 中国
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Quick Overview for NAMPT 抗体 (ABIN967254)

抗原

See all NAMPT 抗体
NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

适用

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克隆类型

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单克隆

标记

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This NAMPT antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 特异性

    Ni-NTA purified truncated recombinant Visfatin expressed in E. Coli strain BL21 (DE3)

    纯化方法

    Antibodies are purified by protein A affinity chromatography

    亚型

    IgG1
  • 应用备注

    Western Blot: Dilution 1: 2,00- 1: 1,000
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 储存条件

    -20 °C
  • Jin, Zhuo, Guo, Field: "p21-activated Kinase 1 (Pak1)-dependent phosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylation of BAD, and Bcl-2 association." in: The Journal of biological chemistry, Vol. 280, Issue 26, pp. 24698-705, (2005) (PubMed).

    Antignani, Youle: "A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad." in: Biochemistry, Vol. 44, Issue 10, pp. 4074-82, (2005) (PubMed).

  • 抗原

    NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

    别名

    Visfatin

    背景

    Visfatin, a newly identified adipocytokine ,which is predominantly secreted from visceral adipose tissue both in humans and mice . Visfatin corresponds to a protein identified previously as pre-B cell colony-enhancing factor (PBEF). Visfatin exerted insulin-mimetic effects in cultured cells, various insulin-sensitive tissues such as liver, muscle, and fat ,and lowered plasma glucose levels in mice. Mice heterozygous for a targeted mutation in the visfatin gene had modestly higher levels of plasma glucose relative to wild-type littermates. visfatin binds to and activates the insulin receptor. Which may lead to new insights into glucose homeostasis and/or new therapies for metabolic disorders such as diabetes.

    基因ID

    10135
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