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SLUG 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects SLUG in IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠. It has been mentioned in 5+ publications
产品编号 ABIN967057
发货至: 中国
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Quick Overview for SLUG 抗体 (C-Term) (ABIN967057)

抗原

See all SLUG (SNAI2) 抗体
SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))

适用

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人, 小鼠, 大鼠

宿主

  • 39
  • 11

克隆类型

  • 40
  • 9
多克隆

标记

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This SLUG antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    免疫原

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to near C-terminal residues of human SNAI2
  • 限制

    仅限研究用
  • 储存条件

    4 °C
  • Larriba, Martín-Villar, García, Pereira, Peña, de Herreros, Bonilla, Muñoz: "Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer." in: Carcinogenesis, Vol. 30, Issue 8, pp. 1459-68, (2009) (PubMed).

    Wang, Wang, Chang, Wu, Chao, Kao, Yuan, Lin, Yang, Chan, Li, Hong, Yang: "p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug." in: Nature cell biology, Vol. 11, Issue 6, pp. 694-704, (2009) (PubMed).

    Saegusa, Hashimura, Kuwata, Okayasu: "Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug." in: The American journal of pathology, Vol. 174, Issue 6, pp. 2107-15, (2009) (PubMed).

    Hemavathy, Guru, Harris, Chen, Ip: "Human Slug is a repressor that localizes to sites of active transcription." in: Molecular and cellular biology, Vol. 20, Issue 14, pp. 5087-95, (2000) (PubMed).

    Inukai, Inoue, Kurosawa, Goi, Shinjyo, Ozawa, Mao, Inaba, Look: "SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein." in: Molecular cell, Vol. 4, Issue 3, pp. 343-52, (1999) (PubMed).

  • 抗原

    SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))

    别名

    SNAI2

    背景

    SNAI2 is a member of the Snail family of C2H2-type zinc finger transcription factors. The SNAI2 protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress Ecadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this SNAI2 gene may be associated with sporatic cases of neural tube defects.
    Synonyms: MGC10182, SLUG, SLUGH1, WS2D
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