SLUG 抗体
(2 references)Quick Overview for SLUG 抗体 (ABIN967056)
抗原
See all SLUG (SNAI2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
纯化方法
- Ascitic fluid
-
免疫原
- Purified recombinant fragment of human SNAI2 expressed in E. Coli.
-
亚型
- IgG1
-
-
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 97-169) antibody
SNAI2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C12 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 100-200) antibodySNAI2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4B6D5 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 97-169) antibodySNAI2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 98-129) antibodySNAI2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 89-268) antibodySNAI2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 126-268) antibodySNAI2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) antibodySNAI2 适用: 人 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 69-132) antibodySNAI2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 116-148), (Middle Region) antibodySNAI2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (Middle Region) antibodySNAI2 适用: 人, 小鼠, 大鼠, Cow, 绵羊, 犬, 马, 兔, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
-
-
: "Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug." in: The American journal of pathology, Vol. 174, Issue 6, pp. 2107-15, (2009) (PubMed).
: "Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3." in: Molecular biology of the cell, Vol. 19, Issue 11, pp. 4875-87, (2008) (PubMed).
-
: "Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug." in: The American journal of pathology, Vol. 174, Issue 6, pp. 2107-15, (2009) (PubMed).
-
- SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
-
别名
- SNAI2
-
背景
-
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity.The tumor suppressor protein p53 induces Slug expression in alpha-irradiated cells, Slug protects damaged cells from apoptosis by repressing p53-induced transcription of the proapoptotic Bcl-2 family protein Puma. Mutations in this gene may be associated with sporatic cases of neural tube defects.
Synonyms: SLUG, WS2D, SLUGH1, MGC10182, SNAI2 -
分子量
- 30kDa
-
基因ID
- 6591
抗原
-
