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RPS6KA1 抗体

RPS6KA1 适用: 人 WB, ELISA, IHC Monoclonal unconjugated
产品编号 ABIN966976
发货至: 中国
  • 抗原 See all RPS6KA1 抗体
    RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
    适用
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    克隆类型
    • 190
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    单克隆
    标记
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    This RPS6KA1 antibody is un-conjugated
    应用范围
    • 181
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Crude ascites.
    免疫原
    Ni-NTA purified truncated recombinant RSK1 expressed in E. Coli strain BL21 (DE3)
    亚型
    IgG2a
    Top Product
    Discover our top product RPS6KA1 Primary Antibody
  • 应用备注
    Western Blot: 1: 500- 1: 2,000
    IHC(P): 1: 500- 1: 2,000
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 储存条件
    -20 °C
  • 抗原
    RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
    别名
    RSK1 (RPS6KA1 产品)
    别名
    HU-1 antibody, MAPKAPK1A antibody, RSK antibody, RSK1 antibody, Rsk1 antibody, p90rsk antibody, rsk antibody, RPS6KA antibody, hu-1 antibody, mapkapk1a antibody, rsk1 antibody, wu:fc56h07 antibody, zgc:152654 antibody, ribosomal protein S6 kinase A1 antibody, ribosomal protein S6 kinase polypeptide 1 antibody, ribosomal protein S6 kinase A1-like antibody, ribosomal protein S6 kinase A1 L homeolog antibody, ribosomal protein S6 kinase a, polypeptide 1 antibody, RPS6KA1 antibody, Rps6ka1 antibody, RPS6KA1L antibody, rps6ka1.L antibody, rps6ka1 antibody
    背景
    Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB. RSK proteins possess two separate kinase domains, the C terminal kinase domain and the N terminal kinase domain, separated by a linker region containing a hydrophobic motif. RSK is activated by many stimuli including growth factors, phorbol esters, cAMP, heat shock, and irradiation.
    基因ID
    6195
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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