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RPS6KA1 抗体 (pThr359)

RPS6KA1 适用: 人 WB, DB 宿主: 兔 Polyclonal RB13385 unconjugated
产品编号 ABIN1881765
发货至: 中国
  • 抗原 See all RPS6KA1 抗体
    RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
    抗原表位
    • 40
    • 30
    • 25
    • 18
    • 16
    • 15
    • 14
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 3
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    pThr359
    适用
    • 202
    • 123
    • 91
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 212
    • 17
    克隆类型
    • 189
    • 41
    多克隆
    标记
    • 106
    • 17
    • 14
    • 11
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    This RPS6KA1 antibody is un-conjugated
    应用范围
    • 181
    • 101
    • 54
    • 53
    • 50
    • 27
    • 22
    • 22
    • 12
    • 12
    • 8
    • 3
    • 2
    • 1
    Western Blotting (WB), Dot Blot (DB)
    预测反应
    C, X
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This RPS6KA1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T359 of human RPS6KA1.
    克隆位点
    RB13385
    亚型
    Ig Fraction
    Top Product
    Discover our top product RPS6KA1 Primary Antibody
  • 应用备注
    WB: 1:2000. DB: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Roux, Ballif, Anjum, Gygi, Blenis: "Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 37, pp. 13489-94, (2004) (PubMed).

    Bohuslav, Chen, Kwon, Mu, Greene: "p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1." in: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26115-25, (2004) (PubMed).

    Hu, Fang, Dunham, Prada, Stachowiak, Stachowiak: "90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling." in: The Journal of biological chemistry, Vol. 279, Issue 28, pp. 29325-35, (2004) (PubMed).

    Fernando, Wimalasena: "Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and Akt." in: Molecular biology of the cell, Vol. 15, Issue 7, pp. 3266-84, (2004) (PubMed).

  • 抗原
    RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
    别名
    RPS6KA1 (RPS6KA1 产品)
    别名
    HU-1 antibody, MAPKAPK1A antibody, RSK antibody, RSK1 antibody, Rsk1 antibody, p90rsk antibody, rsk antibody, RPS6KA antibody, hu-1 antibody, mapkapk1a antibody, rsk1 antibody, wu:fc56h07 antibody, zgc:152654 antibody, ribosomal protein S6 kinase A1 antibody, ribosomal protein S6 kinase polypeptide 1 antibody, ribosomal protein S6 kinase A1-like antibody, ribosomal protein S6 kinase A1 L homeolog antibody, ribosomal protein S6 kinase a, polypeptide 1 antibody, RPS6KA1 antibody, Rps6ka1 antibody, RPS6KA1L antibody, rps6ka1.L antibody, rps6ka1 antibody
    背景
    RPS6KA1 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation.
    分子量
    82723
    NCBI登录号
    NP_001006666, NP_002944
    UniProt
    Q15418
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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