PPARG 抗体
Quick Overview for PPARG 抗体 (ABIN966887)
抗原
See all PPARG 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Ni-NTA purified truncated recombinant PPARG expressed in E. Coli strain BL21 (DE3)
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纯化方法
- Crude ascites.
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亚型
- IgG1
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应用备注
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Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
IF : 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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状态
- Liquid
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储存条件
- -20 °C
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: "Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis." in: Kidney international, Vol. 69, Issue 10, pp. 1756-64, (2006) (PubMed).
: "Beyond peroxisome proliferator-activated receptor gamma signaling: the multi-facets of the antitumor effect of thiazolidinediones." in: Endocrine-related cancer, Vol. 13, Issue 2, pp. 401-13, (2006) (PubMed).
: "Transforming growth factor-beta inhibits CCAAT/enhancer-binding protein expression and PPARgamma activity in unloaded bone marrow stromal cells." in: Experimental cell research, Vol. 303, Issue 1, pp. 138-47, (2004) (PubMed).
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: "Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis." in: Kidney international, Vol. 69, Issue 10, pp. 1756-64, (2006) (PubMed).
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- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
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别名
- PPARG
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背景
- PPAR gamma(PPARG), which encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. Three subtypes of PPARs are known: PPAR-alpha, PPARdelta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
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基因ID
- 5468
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途径
- MAPK Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
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