JAK2 抗体
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北京 101111
Quick Overview for JAK2 抗体 (ABIN966432)
抗原
See all JAK2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- JAK2 (Ab-221) antibody detects endogenous levels of total JAK2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized non-phosphopeptide derived from human JAK2 around the phosphorylation site of tyrosine 221 (Q-D-YP-H-I).
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应用备注
- IHC: 1:50-1:100.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100ug/100ul.
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling." in: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4968-78, (2004) (PubMed).
: "Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity." in: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4955-67, (2004) (PubMed).
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- JAK2 (Janus Kinase 2 (JAK2))
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别名
- JAK2
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途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
抗原
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