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JAK2 抗体 (C-Term)

JAK2 适用: 人, 小鼠 WB, FACS, IF 宿主: 兔 Polyclonal RB02956 unconjugated
产品编号 ABIN387982
发货至: 中国
  • 抗原 See all JAK2 抗体
    JAK2 (Janus Kinase 2 (JAK2))
    抗原表位
    • 37
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    AA 1101-1132, C-Term
    适用
    • 171
    • 100
    • 97
    • 18
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    • 3
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    • 1
    人, 小鼠
    宿主
    • 173
    • 6
    • 2
    克隆类型
    • 158
    • 23
    多克隆
    标记
    • 91
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    This JAK2 antibody is un-conjugated
    应用范围
    • 129
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    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This JAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1101-1132 amino acids from the C-terminal region of human JAK2.
    克隆位点
    RB02956
    亚型
    Ig Fraction
    Top Product
    Discover our top product JAK2 Primary Antibody
  • 应用备注
    IF: 1:10~50. WB: 1:1000. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Feng, Chen, Wang, Cheng, Zou, Zhong, Xu: "Roflumilast reverses polymicrobial sepsis-induced liver damage by inhibiting inflammation in mice." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 97, Issue 9, pp. 1008-1019, (2017) (PubMed).

    Zhao, Li, Liao, Luo, Shi, Feng, Chen: "Evodiamine Induces Apoptosis and Inhibits Migration of HCT-116 Human Colorectal Cancer Cells." in: International journal of molecular sciences, Vol. 16, Issue 11, pp. 27411-21, (2015) (PubMed).

    Kanda, Watanabe: "Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes." in: Endocrinology, Vol. 148, Issue 5, pp. 2317-25, (2007) (PubMed).

  • 抗原
    JAK2 (Janus Kinase 2 (JAK2))
    别名
    JAK2 (JAK2 产品)
    别名
    JAK2bCA antibody, jak2 antibody, JTK10 antibody, THCYT3 antibody, AI504024 antibody, C81284 antibody, Fd17 antibody, JAK-2 antibody, Janus kinase 2b antibody, Janus kinase 2 antibody, jak2b antibody, JAK2 antibody, Jak2 antibody
    背景
    This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
    分子量
    130674
    基因ID
    3717
    NCBI登录号
    NP_004963
    UniProt
    O60674
    途径
    JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
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