JAK2 抗体 (AA 745-955)
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北京 101111
Quick Overview for JAK2 抗体 (AA 745-955) (ABIN966429)
抗原
See all JAK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 745-955
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of JAK2(745-955aa) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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状态
- Liquid
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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: "Contributions of leukemia inhibitory factor receptor and oncostatin M receptor to signal transduction in heterodimeric complexes with glycoprotein 130." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 12, pp. 6651-8, (2000) (PubMed).
: "The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity." in: The Journal of biological chemistry, Vol. 274, Issue 44, pp. 31531-42, (1999) (PubMed).
: "Plasma levels of lipid and cholesterol oxidation products and cytokines in diabetes mellitus and cigarette smoking: effects of vitamin E treatment." in: Atherosclerosis, Vol. 129, Issue 2, pp. 169-76, (1997) (PubMed).
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- JAK2 (Janus Kinase 2 (JAK2))
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别名
- JAK2
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背景
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This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
Synonyms: JTK10, JAK2 -
分子量
- 130.6kDa
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基因ID
- 3717
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途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
抗原
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