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IL-18 抗体 (C-Term)

IL18 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN966391
发货至: 中国
  • 抗原 See all IL-18 (IL18) 抗体
    IL-18 (IL18) (Interleukin 18 (IL18))
    抗原表位
    • 30
    • 10
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 67
    • 37
    • 31
    • 6
    • 5
    • 4
    • 4
    • 3
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    • 1
    • 1
    • 1
    宿主
    • 105
    • 23
    • 1
    • 1
    • 1
    克隆类型
    • 103
    • 24
    • 2
    多克隆
    标记
    • 63
    • 16
    • 12
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This IL-18 antibody is un-conjugated
    应用范围
    • 78
    • 45
    • 34
    • 31
    • 26
    • 25
    • 12
    • 11
    • 10
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Interleukin-18 (IL18) detection. Tested with WB in Human.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminal of Human IL18.< br/>Immunogen was affinity purified.
    亚型
    IgG
    Top Product
    Discover our top product IL18 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
  • 抗原
    IL-18 (IL18) (Interleukin 18 (IL18))
    别名
    Interleukin-18 (IL18 产品)
    别名
    Igif antibody, Il-18 antibody, IL-18 antibody, IGIF antibody, ChIL-18 antibody, IL-1g antibody, IL1F4 antibody, IL18 antibody, interleukin 18 antibody, Il18 antibody, IL18 antibody
    背景
    Interleukin-18 also known as IL18 is a protein which in humans is encoded by the IL18 gene. The protein encoded by this gene is a proinflammatory cytokine. IL-18 is a cytokine produced by macrophages and other cells that belongs to the IL-1 superfamily. IL-18 works by binding to the interleukin-18 receptor, and together with IL-12 it induces cell-mediated immunity following infection with microbial products like lipopolysaccharide (LPS). After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-gamma (IFN-gamma) or type II interferon that plays an important role in activating the macrophages or other cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production in B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. The human interleukin 18 gene IL18 maps to 11q22. 2-q22. 3, closely linked to the DRD2 gene locus and distinct from mapped IDDM loci.
    途径
    Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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