HSP27 抗体
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北京 101111
Quick Overview for HSP27 抗体 (ABIN966313)
抗原
See all HSP27 (HSPB1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- HSP27 (Ab-78) antibody detects endogenous levels of total HSP27 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized phosphopeptide derived from human HSP27 around the phosphorylation site of serine 78 (A-L-SP-R-Q).
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应用备注
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WB: 1:500~1:1000
IHC: 1:50~1:100. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100ug/100ul.
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "Tropomyosin interacts with phosphorylated HSP27 in agonist-induced contraction of smooth muscle." in: American journal of physiology. Cell physiology, Vol. 286, Issue 6, pp. C1290-301, (2004) (PubMed).
: "Control of functional systems in the brainstem and spinal cord." in: Current opinion in neurobiology, Vol. 2, Issue 6, pp. 794-801, (1993) (PubMed).
: "Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II." in: The Journal of biological chemistry, Vol. 267, Issue 2, pp. 794-803, (1992) (PubMed).
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- HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
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别名
- HSP27
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途径
- MAPK Pathway, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling
抗原
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