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HSP27 抗体

This 兔 多克隆 antibody specifically detects HSP27 in IHC. It exhibits reactivity toward 人. It has been mentioned in 3+ publications
产品编号 ABIN966313
发货至: 中国
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Quick Overview for HSP27 抗体 (ABIN966313)

抗原

See all HSP27 (HSPB1) 抗体
HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

适用

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宿主

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克隆类型

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多克隆

标记

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This HSP27 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 特异性

    HSP27 (Ab-78) antibody detects endogenous levels of total HSP27 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized phosphopeptide derived from human HSP27 around the phosphorylation site of serine 78 (A-L-SP-R-Q).
  • 应用备注

    WB: 1:500~1:1000
    IHC: 1:50~1:100.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100ug/100ul.

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Somara, Bitar: "Tropomyosin interacts with phosphorylated HSP27 in agonist-induced contraction of smooth muscle." in: American journal of physiology. Cell physiology, Vol. 286, Issue 6, pp. C1290-301, (2004) (PubMed).

    Jordan, Brownstone, Noga: "Control of functional systems in the brainstem and spinal cord." in: Current opinion in neurobiology, Vol. 2, Issue 6, pp. 794-801, (1993) (PubMed).

    Landry, Lambert, Zhou, Lavoie, Hickey, Weber, Anderson: "Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II." in: The Journal of biological chemistry, Vol. 267, Issue 2, pp. 794-803, (1992) (PubMed).

  • 抗原

    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

    别名

    HSP27

    途径

    MAPK Pathway, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling
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