(1 reference)-
- 抗原 See all GRK2 (ADRBK1) 抗体
- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
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适用
- 人, 小鼠, 大鼠, 猴
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GRK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human GRK2 expressed in E. Coli.
- 克隆位点
- 3F8
- 亚型
- IgG1
- Top Product
- Discover our top product ADRBK1 Primary Antibody
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anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 440-689) antibody
ADRBK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (C-Term) antibodyKO Validated ADRBK1 适用: 人 WB, IHC (p), IF, ICC, FACS, IP 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) antibodyKO Validated ADRBK1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) antibodyADRBK1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3F8 unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (Internal Region) antibodyADRBK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 633-660), (C-Term) antibodyADRBK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0982 unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (C-Term) antibodyADRBK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (N-Term) antibodyADRBK1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 2-221) antibodyADRBK1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (Ser129) antibodyADRBK1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 状态
- Liquid
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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: "EGF transregulates opioid receptors through EGFR-mediated GRK2 phosphorylation and activation." in: Molecular biology of the cell, Vol. 19, Issue 7, pp. 2973-83, (2008) (PubMed).
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: "EGF transregulates opioid receptors through EGFR-mediated GRK2 phosphorylation and activation." in: Molecular biology of the cell, Vol. 19, Issue 7, pp. 2973-83, (2008) (PubMed).
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- 抗原
- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
- 别名
- GRK2 (ADRBK1 产品)
- 别名
- Adrbk-1 antibody, Bark-1 antibody, GRK2 antibody, betaARK1 antibody, BARK1 antibody, BETA-ARK1 antibody, GRK-2 antibody, Grk2 antibody, beta-adrenergic receptor kinase 1 antibody, G protein-coupled receptor kinase 2 antibody, Tsp_00497 antibody, grk2 antibody, Grk2 antibody, GRK2 antibody
- 背景
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The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of betaadrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
Tissue specificity: Expressed in peripheral blood leukocytes
Synonyms: GRK2, BARK1, FLJ16718, BETA-ARK1, ADRBK1 - 分子量
- 80kDa
- 基因ID
- 156
- 途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
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