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Fibulin 5 抗体

Cited in 3+ publications. This anti-Fibulin 5 antibody is a not_set 单克隆 antibody detecting Fibulin 5 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN966144
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Fibulin 5 抗体 (ABIN966144)

抗原

See all Fibulin 5 (FBLN5) 抗体
Fibulin 5 (FBLN5)

适用

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宿主

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克隆类型

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单克隆

标记

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This Fibulin 5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 特异性

    Ni-NTA purified truncated recombinant Fibulin 5 expressed in E. Coli strain BL21 (DE3)

    纯化方法

    Crude ascites.

    亚型

    IgM
  • 应用备注

    Western Blot: 1: 500- 1: 2000
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    -20 °C
  • Wen, Hochholdinger, Sauer, Bruce, Schnable: "The roothairless1 gene of maize encodes a homolog of sec3, which is involved in polar exocytosis." in: Plant physiology, Vol. 138, Issue 3, pp. 1637-43, (2005) (PubMed).

    Kadoya, Sasaki, Kostka, Timpl, Matsuzaki, Kumagai, Sakai, Nishiyama, Amano: "Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis." in: The British journal of dermatology, Vol. 153, Issue 3, pp. 607-12, (2005) (PubMed).

    Lee, Roy, Mogford, Schiemann, Mustoe: "Fibulin-5 promotes wound healing in vivo." in: Journal of the American College of Surgeons, Vol. 199, Issue 3, pp. 403-10, (2004) (PubMed).

  • 抗原

    Fibulin 5 (FBLN5)

    别名

    Fibulin 5

    背景

    Fibulin 5(FBLN5), with 448-amino acid protein (about 50kDa), is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.

    途径

    SARS-CoV-2 Protein Interactome
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