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Fibulin 5 抗体 (AA 242-448)

FBLN5 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1G6A4 unconjugated
产品编号 ABIN969131
发货至: 中国
  • 抗原 See all Fibulin 5 (FBLN5) 抗体
    Fibulin 5 (FBLN5)
    抗原表位
    • 12
    • 8
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 242-448
    适用
    • 52
    • 30
    • 23
    • 1
    宿主
    • 52
    • 5
    • 1
    小鼠
    克隆类型
    • 53
    • 7
    单克隆
    标记
    • 27
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Fibulin 5 antibody is un-conjugated
    应用范围
    • 55
    • 31
    • 14
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of FBLN5 (aa242-448) expressed in E. coli.
    克隆位点
    1G6A4
    亚型
    IgG1
    Top Product
    Discover our top product FBLN5 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Wang, LeMaire, Chen, Carter, Shen, Gan, Bartsch, Wilks, Utama, Ou, Thompson, Coselli, Wang: "Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection." in: Surgery, Vol. 138, Issue 2, pp. 352-9, (2005) (PubMed).

    Stone, Braun, Russell, Kuehn, Lotery, Moore, Eastman, Casavant, Sheffield: "Missense variations in the fibulin 5 gene and age-related macular degeneration." in: The New England journal of medicine, Vol. 351, Issue 4, pp. 346-53, (2004) (PubMed).

    Markova, Zou, Ringpfeil, Sasaki, Kostka, Timpl, Uitto, Chu: "Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene." in: American journal of human genetics, Vol. 72, Issue 4, pp. 998-1004, (2003) (PubMed).

  • 抗原
    Fibulin 5 (FBLN5)
    别名
    FBLN5 (FBLN5 产品)
    别名
    zgc:103575 antibody, FBLN5 antibody, MGC108414 antibody, Fibulin-5 antibody, DKFZp469K0327 antibody, ADCL2 antibody, ARCL1A antibody, ARMD3 antibody, DANCE antibody, EVEC antibody, FIBL-5 antibody, UP50 antibody, A55 antibody, fibulin 5 antibody, fbln5 antibody, FBLN5 antibody, Fbln5 antibody
    背景

    Description: FBLN5: fibulin 5. The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling.

    Aliases: EVEC, UP50, ARMD3, DANCE

    基因ID
    10516
    HGNC
    10516
    途径
    SARS-CoV-2 Protein Interactome
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