MUC1 抗体 (DTRP (Asp-Thr-Arg-Pro))
Quick Overview for MUC1 抗体 (DTRP (Asp-Thr-Arg-Pro)) (ABIN966067)
抗原
See all MUC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- DTRP (Asp-Thr-Arg-Pro)
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纯化方法
- Concentrated.
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免疫原
- Human Milk Fat Globule Membranes
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亚型
- IgG1 kappa
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应用备注
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Immunohistochemistry: (Paraffin/Frozen): 1:50.
Staining Procedure: Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:50 in IHC. It is recommended that this product be used on frozen tissue sections or specimens. The optimal conditions should be determined by the individual laboratory. -
说明
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Cellular Localization: Cell Membrane, Cytoplasmic.
Recommended Positive Control: Breast Carcinoma -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.3 mg/ml.
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缓冲液
- 20 mM Tris-Borate, 150 mM Sodium Chloride, dialyzed media RPMI 1640/D-MEM containing Fetal Bovine Serum, BMC-6 Carrier Polysaccharides, Carrier Protein, pH 7.5
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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Cell membrane-associated mucins and their adhesion-modulating property." in: Trends in biochemical sciences, Vol. 17, Issue 9, pp. 359-63, (1992) (PubMed).
: "Monoclonal antibodies against human milk-fat globule membranes detecting differentiation antigens of the mammary gland and its tumors." in: International journal of cancer. Journal international du cancer, Vol. 34, Issue 2, pp. 197-206, (1984) (PubMed).
: "
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Cell membrane-associated mucins and their adhesion-modulating property." in: Trends in biochemical sciences, Vol. 17, Issue 9, pp. 359-63, (1992) (PubMed).
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- MUC1 (Mucin 1 (MUC1))
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别名
- EMA
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背景
- Reacts with human high molecular weight sialomucin, episialin, mucin 1 (MUC-1), or polymorphic epithelial mucin (PEM). It recognizes the multiple protein epitope that is relatively insensitive to glycosylation. Therefore, it is very sensitive in the detection of episialin expression in different epithelial tissues.
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分子量
- 265-400 kDa
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基因ID
- 4582
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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