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MUC1 抗体 (DTRP (Asp-Thr-Arg-Pro))

This anti-MUC1 antibody is a 小鼠 单克隆 antibody detecting MUC1 in IHC (p) 和 IHC (fro). Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN966067
发货至: 中国

Quick Overview for MUC1 抗体 (DTRP (Asp-Thr-Arg-Pro)) (ABIN966067)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MUC1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

B24-1 (GP1-4)
  • 抗原表位

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    DTRP (Asp-Thr-Arg-Pro)

    纯化方法

    Concentrated.

    免疫原

    Human Milk Fat Globule Membranes

    亚型

    IgG1 kappa
  • 应用备注

    Immunohistochemistry: (Paraffin/Frozen): 1:50.
    Staining Procedure: Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:50 in IHC. It is recommended that this product be used on frozen tissue sections or specimens. The optimal conditions should be determined by the individual laboratory.

    说明

    Cellular Localization: Cell Membrane, Cytoplasmic.
    Recommended Positive Control: Breast Carcinoma

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.3 mg/ml.

    缓冲液

    20 mM Tris-Borate, 150 mM Sodium Chloride, dialyzed media RPMI 1640/D-MEM containing Fetal Bovine Serum, BMC-6 Carrier Polysaccharides, Carrier Protein, pH 7.5

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Hilkens, Ligtenberg, Vos, Litvinov: "Cell membrane-associated mucins and their adhesion-modulating property." in: Trends in biochemical sciences, Vol. 17, Issue 9, pp. 359-63, (1992) (PubMed).

    Hilkens, Buijs, Hilgers, Hageman, Calafat, Sonnenberg, van der Valk: "Monoclonal antibodies against human milk-fat globule membranes detecting differentiation antigens of the mammary gland and its tumors." in: International journal of cancer. Journal international du cancer, Vol. 34, Issue 2, pp. 197-206, (1984) (PubMed).

  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    EMA

    背景

    Reacts with human high molecular weight sialomucin, episialin, mucin 1 (MUC-1), or polymorphic epithelial mucin (PEM). It recognizes the multiple protein epitope that is relatively insensitive to glycosylation. Therefore, it is very sensitive in the detection of episialin expression in different epithelial tissues.

    分子量

    265-400 kDa

    基因ID

    4582

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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