EGFR 抗体
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北京 101111
Quick Overview for EGFR 抗体 (ABIN966040)
抗原
See all EGFR 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- EGFR (Ab-1070) antibody detects endogenous levels of total EGFR protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized non-phosphopeptide derived from human EGFR around the phosphorylation site of serine1070 (R-Y-SP-S-D).
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应用备注
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WB: 1:500~1:1000
IHC: 1:50~1:100. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100ug/100ul.
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "Ca2+/calmodulin-dependent kinase II phosphorylates the epidermal growth factor receptor on multiple sites in the cytoplasmic tail and serine 744 within the kinase domain to regulate signal generation." in: The Journal of biological chemistry, Vol. 274, Issue 23, pp. 16168-73, (1999) (PubMed).
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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别名
- EGFR
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途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
抗原
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