(4 references)-
- 抗原 See all COX1 抗体
- COX1 (Cytochrome C Oxidase Subunit I (COX1))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for Cytochrome c oxidase subunit 1 (MT-CO1) detection. Tested with WB in Human.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminal of human CO1.< br/>Immunogen was affinity purified.
- 亚型
- IgG
- Top Product
- Discover our top product COX1 Primary Antibody
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anti-Cytochrome C Oxidase Subunit I (COX1) (AA 2-14), (N-Term) antibody
COX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit I (COX1) (AA 318-599) antibodyCOX1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit I (COX1) (AA 401-500) antibodyCOX1 适用: 小鼠, 大鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit I (COX1) (AA 1-160) antibodyCOX1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit I (COX1) (AA 474-513) antibodyCOX1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit I (COX1) (C-Term) antibodyCOX1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit I (COX1) (AA 195-224) antibodyCOX1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB24524 unconjugated
anti-Cytochrome C Oxidase Subunit I (COX1) (C-Term) antibodyCOX1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit I (COX1) (AA 550-599) antibodyCOX1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Sodium azide, Thimerosal (Merthiolate)
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
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: "An intragenic suppressor in the cytochrome c oxidase I gene of mouse mitochondrial DNA." in: Human molecular genetics, Vol. 12, Issue 3, pp. 329-39, (2003) (PubMed).
: "Heterozygous mutations of the kinesin KIF21A in congenital fibrosis of the extraocular muscles type 1 (CFEOM1)." in: Nature genetics, Vol. 35, Issue 4, pp. 318-21, (2003) (PubMed).
: "Insight into the active-site structure and function of cytochrome oxidase by analysis of site-directed mutants of bacterial cytochrome aa3 and cytochrome bo." in: Journal of bioenergetics and biomembranes, Vol. 25, Issue 2, pp. 121-36, (1993) (PubMed).
: "Separation of mammalian cytochrome c oxidase into 13 polypeptides by a sodium dodecyl sulfate-gel electrophoretic procedure." in: Analytical biochemistry, Vol. 129, Issue 2, pp. 517-21, (1983) (PubMed).
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: "An intragenic suppressor in the cytochrome c oxidase I gene of mouse mitochondrial DNA." in: Human molecular genetics, Vol. 12, Issue 3, pp. 329-39, (2003) (PubMed).
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- 抗原
- COX1 (Cytochrome C Oxidase Subunit I (COX1))
- 别名
- Cytochrome c oxidase subunit 1 (COX1 产品)
- 别名
- COX-1 antibody, COI antibody, MTCO1 antibody, COX1 antibody, CoxI antibody, prostaglandin-endoperoxide synthase 1 antibody, cytochrome c oxidase subunit I antibody, cytochrome c oxidase subunit 1 antibody, cytochrome c oxidase 1 antibody, PTGS1 antibody, COX1 antibody, cox1 antibody
- 背景
- Cytochrome c oxidase subunit I (CO1 or MTCO1) is 1 of 3 mitochondrial DNA (mtDNA) encoded subunits (MTCO1, MTCO2, MTCO3) of respiratory Complex IV. Complex IV is located within the mitochondrial inner membrane and is the third and final enzyme of the electron transport chain of mitochondrial oxidative phosphorylation. It is composed of 13 polypeptides. Subunits I, II, and III (MTCO1, MTCO2, MTCO3) are encoded by mtDNA while subunits IV, Va, Vb, VIa, VIb, VIc, VIIa, VIIb, VIIc, and VIII are nuclear encoded. The cytochrome c oxidase family of enzymes have 4 redox centers, 2 hemes and 2 copper centers. In mitochondrial Complex IV, the 2 hemes are a and a3 and the 2 coppers are CuA and CuB. The 2 hemes and CuB are bound to subunit I. Acin-Perez et al. (2003) identified a cell line containing single and double missense mutations in the cytochrome c oxidase (COX) subunit I gene of mouse mitochondrial DNA. And they hypothesized that deleterious mutations can arise and become predominant, cultured cells can maintain several mtDNA haplotypes at stable frequencies, the respiratory chain has little spare COX capacity, and that the size of a cavity in the vicinity of val421 in MTCO1I of animal COX may affect the function of the enzyme.
- 途径
- Proton Transport
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