CREB1 抗体 (cAMP Responsive Element Binding Protein 1)

Details for Product anti-CREB1 Antibody No. ABIN965928
抗原
  • creb
  • CREB1
  • Creb1
  • CREB
  • 2310001E10Rik
  • 3526402H21Rik
  • AV083133
  • Creb
  • Creb-1
  • creb1
  • zgc:55598
  • cAMP responsive element binding protein 1
  • cAMP responsive element binding protein
  • cAMP responsive element binding protein 1 S homeolog
  • cAMP responsive element binding protein 1a
  • CREB1
  • creb1
  • CREB
  • Creb1
  • creb1.S
  • creb1a
适用
人, 小鼠, 猴, 大鼠
621
388
349
42
37
35
33
26
23
21
16
14
13
6
6
6
1
1
1
1
1
宿主
小鼠
553
71
12
1
克隆类型 (克隆位点)
单克隆 ()
标记
This CREB1 antibody is un-conjugated
26
15
15
14
13
13
13
13
13
8
7
6
3
3
3
3
3
1
应用范围
Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
452
269
223
95
84
57
42
40
27
18
11
10
5
3
2
2
1
1
选项
免疫原 Purified recombinant fragment of human CREB1 expressed in E. Coli.
克隆位点 5G3
亚型 IgG1
纯化方法 Ascitic fluid
Plasmids, Primers & others Plasmids, Primers & others CREB1 products on genomics-online (e.g. as negative or positive controls)
抗原
别名 CREB1 (CREB1 Antibody 摘要)
背景 This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
Synonyms: CREB, MGC9284, CREB1
分子量 43kDa
基因ID 1385
途径 TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
应用备注 Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
限制 仅限研究用
状态 Liquid
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C
有引用在: Jansson, Ng, Fu, Depatie, Al Azzabi, Screaton: "Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 29, pp. 10161-6, 2008 (PubMed).

Seo, Chung: "CREB activates proteasomal degradation of DSCR1/RCAN1." in: FEBS letters, Vol. 582, Issue 13, pp. 1889-93, 2008 (PubMed).

背景 Mamdani, Alda, Grof, Young, Rouleau, Turecki: "Lithium response and genetic variation in the CREB family of genes." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 4, pp. 500-4, 2008 (PubMed).

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