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CDK2 抗体

This anti-CDK2 antibody is a 兔 多克隆 antibody detecting CDK2 in IHC. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN965843
发货至: 中国

Quick Overview for CDK2 抗体 (ABIN965843)

抗原

See all CDK2 抗体
CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CDK2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 特异性

    CDK2 (Ab-160) antibody detects endogenous levels of total CDK2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized non-phosphopeptide derived from human CDK2 around the phosphorylation site of threonine160 (T-Y-TP-H-E).
  • 应用备注

    WB: 1:500~1:1000.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100ug/100ul.

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Liu, Wu, Galaktionov: "p42, a novel cyclin-dependent kinase-activating kinase in mammalian cells." in: The Journal of biological chemistry, Vol. 279, Issue 6, pp. 4507-14, (2004) (PubMed).

    Ukomadu, Dutta: "Inhibition of cdk2 activating phosphorylation by mevastatin." in: The Journal of biological chemistry, Vol. 278, Issue 7, pp. 4840-6, (2003) (PubMed).

    Morris, Gondeau, Tainer, Divita: "Kinetic mechanism of activation of the Cdk2/cyclin A complex. Key role of the C-lobe of the Cdk." in: The Journal of biological chemistry, Vol. 277, Issue 26, pp. 23847-53, (2002) (PubMed).

    Brown, Noble, Lawrie, Morris, Tunnah, Divita, Johnson, Endicott: "Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity." in: The Journal of biological chemistry, Vol. 274, Issue 13, pp. 8746-56, (1999) (PubMed).

  • 抗原

    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

    别名

    CDK2

    途径

    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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