CDK2 抗体 (AA 81-298)
(12 references)-
- 抗原 See all CDK2 抗体
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
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抗原表位
- AA 81-298
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Cyclin-dependent kinase 2(CDK2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Cyclin-dependent kinase 2(CDK2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: cyclin-dependent kinase 2
Protein Name: Cyclin-dependent kinase 2 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human Cdk2 recombinant protein (Position: E81-L298). Human Cdk2 shares 98.6% amino acid (aa) sequence identity with rat Cdk2.
- 亚型
- IgG
- Top Product
- Discover our top product CDK2 Primary Antibody
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anti-Cyclin-Dependent Kinase 2 (CDK2) antibody
CDK2 适用: 人, 小鼠 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1A6 unconjugated
anti-Cyclin-Dependent Kinase 2 (CDK2) (AA 211-298) antibodyCDK2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2E8 unconjugated
anti-Cyclin-Dependent Kinase 2 (CDK2) antibodyCDK2 适用: 人, 猴 WB, FACS, IF 宿主: 小鼠 Monoclonal 4B4 unconjugated
anti-Cyclin-Dependent Kinase 2 (CDK2) (AA 197-295) antibodyCDK2 适用: 人, 小鼠 WB, IHC, ELISA, FACS, IF 宿主: 小鼠 Monoclonal 1A6 unconjugated
anti-Cyclin-Dependent Kinase 2 (CDK2) antibodyCDK2 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 2 (CDK2) (AA 1-298) antibodyCDK2 适用: 人 WB, IHC, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 2 (CDK2) antibodyCDK2 适用: 人, 猴 WB, FACS, IF 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-Cyclin-Dependent Kinase 2 (CDK2) (AA 94-198) antibodyCDK2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 2 (CDK2) (AA 93-211) antibodyCDK2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 2 (CDK2) (AA 1-298) antibodyCDK2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Circulating exosomal microRNAs reveal the mechanism of Fructus Meliae Toosendan-induced liver injury in mice." in: Scientific reports, Vol. 8, Issue 1, pp. 2832, (2018) (PubMed).
: "Grape Seed Proanthocyanidin Extract Prevents Ovarian Aging by Inhibiting Oxidative Stress in the Hens." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 9390810, (2018) (PubMed).
: "TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells." in: Scientific reports, Vol. 6, pp. 23775, (2017) (PubMed).
: "Effects of tripterygium glycosides on restenosis following endovascular treatment." in: Molecular medicine reports, Vol. 13, Issue 6, pp. 4959-68, (2017) (PubMed).
: "Tubeimoside-1 induces oxidative stress-mediated apoptosis and G0/G1 phase arrest in human prostate carcinoma cells in vitro." in: Acta pharmacologica Sinica, Vol. 37, Issue 7, pp. 950-62, (2017) (PubMed).
: "Rheum emodin inhibits enterovirus 71 viral replication and affects the host cell cycle environment." in: Acta pharmacologica Sinica, Vol. 38, Issue 3, pp. 392-401, (2017) (PubMed).
: "Isoflavone lupiwighteone induces cytotoxic, apoptotic, and antiangiogenic activities in DU-145 prostate cancer cells." in: Anti-cancer drugs, Vol. 26, Issue 6, pp. 599-611, (2015) (PubMed).
: "Platycodin D induces tumor growth arrest by activating FOXO3a expression in prostate cancer in vitro and in vivo." in: Current cancer drug targets, Vol. 14, Issue 9, pp. 860-71, (2015) (PubMed).
: "Enterovirus 71 mediates cell cycle arrest in S phase through non-structural protein 3D." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 3, pp. 425-36, (2015) (PubMed).
: "Design, synthesis and biological evaluation of N-alkyl or aryl substituted isoindigo derivatives as potential dual cyclin-dependent kinase 2 (CDK2)/glycogen synthase kinase 3? (GSK-3?) ..." in: European journal of medicinal chemistry, Vol. 86, pp. 165-74, (2014) (PubMed).
: "The effects of urokinase-type plasminogen activator (uPA) on cell proliferation and phenotypic transformation of rat mesangial cells induced by high glucose." in: Diabetes research and clinical practice, Vol. 103, Issue 3, pp. 489-95, (2014) (PubMed).
: "XJW20, a novel oxoindole derivative, induces G2/M arrest and apoptosis selectively in K562 leukemia cell line." in: Chemico-biological interactions, Vol. 183, Issue 1, pp. 133-41, (2009) (PubMed).
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: "Circulating exosomal microRNAs reveal the mechanism of Fructus Meliae Toosendan-induced liver injury in mice." in: Scientific reports, Vol. 8, Issue 1, pp. 2832, (2018) (PubMed).
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- 抗原
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
- 别名
- CDK2 (CDK2 产品)
- 别名
- p33(CDK2) antibody, A630093N05Rik antibody, wu:fa10c02 antibody, zgc:56598 antibody, zgc:77684 antibody, eg1 antibody, CDKN2 antibody, cdk2L antibody, cyclin dependent kinase 2 antibody, cyclin-dependent kinase 2 antibody, cyclin-dependent kinase 2 S homeolog antibody, CDK2 antibody, Cdk2 antibody, cdk2 antibody, cdk2.S antibody
- 背景
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CDK2, Cyclin-Dependent Kinase2, is also known as P33. The CDK2 protein was highly homologous to p34(CDC2) kinase and more significantly homologous to Xenopus Eg1 kinase, suggesting that CDK2 is the human homolog of Eg1. The CDK2 gene is mapped to 12q13, the same region to which the CDK4 gene maps. Human cyclin A binds independently to 2 kinases, p34(cdc2) or p33. In adenovirus-transformed cells, the viral E1A oncoprotein seems to associate with p33/cyclin A but not with p34(cdc2)/cyclin A. The gene for p33 shares 65 % sequence identity with p34(cdc2). P33(cdk2) plays a unique role in cell cycle regulation of vertebrate cells.
Synonyms: Cdc2 related protein kinase antibody|cdc2-related protein kinase antibody|Cdk 2 antibody| CDK2 antibody|CDK2_HUMAN antibody|Cell devision kinase 2 antibody|Cell division kinase 2 antibody|Cell division protein kinase 2 antibody|Cyclin dependent kinase 2 antibody|cyclin dependent kinase 2-alpha antibody|Cyclin-dependent kinase 2 antibody|p33 protein kinase antibody|p33(CDK2) antibody - 基因ID
- 1017
- UniProt
- P24941
- 途径
- PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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