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CD31 抗体

This anti-CD31 antibody is a 单克隆 antibody detecting CD31 in WB, IHC 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN965785
发货至: 中国

Quick Overview for CD31 抗体 (ABIN965785)

抗原

See all CD31 (PECAM1) 抗体
CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

适用

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克隆类型

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单克隆

标记

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This CD31 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 特异性

    Ni-NTA purified recombinant CD31 expressed in E. Coli strain BL21 (DE3)

    纯化方法

    Antibodies are purified by protein A affinity chromatography

    亚型

    IgG1
  • 应用备注

    Western Blot: 1: 500- 1: 2,000
    IHC(P): 1: 500- 1: 2,000
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 储存条件

    -20 °C
  • Mayr, Zou, Zhang, Dietrich, Hu, Xu: "Accelerated arteriosclerosis of vein grafts in inducible NO synthase(-/-) mice is related to decreased endothelial progenitor cell repair." in: Circulation research, Vol. 98, Issue 3, pp. 412-20, (2006) (PubMed).

    Bingle, Lewis, Corke, Reed, Brown: "Macrophages promote angiogenesis in human breast tumour spheroids in vivo." in: British journal of cancer, Vol. 94, Issue 1, pp. 101-7, (2006) (PubMed).

    Wynne, Ball, McLellan, Dockery, Zimmermann, Moore: "Mouse pregnancy-specific glycoproteins: tissue-specific expression and evidence of association with maternal vasculature." in: Reproduction (Cambridge, England), Vol. 131, Issue 4, pp. 721-32, (2006) (PubMed).

  • 抗原

    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

    别名

    CD31

    背景

    CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors.It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. The antibody reacts with the murine form of the Platelet-Endothelial Cell Adhesion Molecule. The reactivity of the antibody is restricted to the isoform of the molecule that is selectively expressed by endothelial cells.The antigen is predominantly present at the lateral borders of endothelial cells as described for human PECAM-1.It is also weakly expressed on many peripheral lymphoid cells and platelets. CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).

    基因ID

    5175

    途径

    Regulation of Actin Filament Polymerization
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