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CD31 抗体 (AA 28-382)

PECAM1 适用: 人, 大鼠 FACS, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043601
发货至: 中国
  • 抗原 See all CD31 (PECAM1) 抗体
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    抗原表位
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    AA 28-382
    适用
    • 268
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    • 28
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    人, 大鼠
    宿主
    • 151
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    • 7
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    克隆类型
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    • 132
    • 1
    多克隆
    标记
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    This CD31 antibody is un-conjugated
    应用范围
    • 216
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    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Platelet endothelial cell adhesion molecule(PECAM1) detection. Tested with WB, IHC-P, FCM in Human.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Platelet endothelial cell adhesion molecule(PECAM1) detection. Tested with WB, IHC-P, FCM in Human.
    Gene Name: platelet/endothelial cell adhesion molecule 1
    Protein Name: Platelet endothelial cell adhesion molecule
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human CD31 recombinant protein (Position: Q28-G382). Human CD31 shares 65% and 68% amino acid (aa) sequences identity with mouse and rat CD31, respectively.
    亚型
    IgG
    Top Product
    Discover our top product PECAM1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for CD31 is approximately 0.25 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Flow Cytometry: Concentration:1-3 μg/1x106 cells, Tested Species: Human
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Zhang, Chen, Wang, Yang, Li, Wang, Liu, Ye: "Treatment of diabetes mellitus-induced erectile dysfunction using endothelial progenitor cells genetically modified with human telomerase reverse transcriptase." in: Oncotarget, Vol. 7, Issue 26, pp. 39302-39315, (2018) (PubMed).

    Chen, Li, Peng, Jie, Dongye, Cai, Feng, Li, Zeng, Lun, Chen, Xu: "The induction of autophagy against mitochondria-mediated apoptosis in lung cancer cells by a ruthenium (II) imidazole complex." in: Oncotarget, Vol. 7, Issue 49, pp. 80716-80734, (2018) (PubMed).

    Zhang, Peng, Yuan, Xie, Yang, Xue: "Peroxisome proliferator‑activated receptor γ mediates porcine placental angiogenesis through hypoxia inducible factor‑, vascular endothelial growth factor‑ and angiopoietin‑mediated signaling." in: Molecular medicine reports, Vol. 16, Issue 3, pp. 2636-2644, (2018) (PubMed).

    Fan, Qu, Chu, Gao, Gao, Chen, Tian: "MicroRNA-210 promotes angiogenesis in acute myocardial infarction." in: Molecular medicine reports, Vol. 17, Issue 4, pp. 5658-5665, (2018) (PubMed).

    Atala: "Re: Treatment of Diabetes Mellitus-Induced Erectile Dysfunction Using Endothelial Progenitor Cells Genetically Modified with Human Telomerase Reverse Transcriptase." in: The Journal of urology, Vol. 197, Issue 2, pp. 494, (2017) (PubMed).

    Zhou, He, Liu, Feng, Zhang, Hua, Tang: "Angiogenic gene-modified myoblasts promote vascularization during repair of skeletal muscle defects." in: Journal of tissue engineering and regenerative medicine, Vol. 9, Issue 12, pp. 1404-16, (2016) (PubMed).

    Chen, Yu, Gumireddy, Li, Yao, Gao, Chen, Hao, Wang, Huang, Xu, Ye: "ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer." in: Oncotarget, Vol. 6, Issue 9, pp. 6959-76, (2016) (PubMed).

    Wang, Yang, Tang, Long, Huang: "Wound Dressing Model of Human Umbilical Cord Mesenchymal Stem Cells-Alginates Complex Promotes Skin Wound Healing by Paracrine Signaling." in: Stem cells international, Vol. 2016, pp. 3269267, (2016) (PubMed).

    Zhang, Wang, Yang, Pan, Li, Yuan: "Preclinical pharmacodynamic evaluation of antibiotic nitroxoline for anticancer drug repurposing." in: Oncology letters, Vol. 11, Issue 5, pp. 3265-3272, (2016) (PubMed).

    Zeng, Zhao, Ouyang, Zhao, Zhang, Chen, Yu, Lei: "Label-retaining assay enriches tumor-initiating cells in glioblastoma spheres cultivated in serum-free medium." in: Oncology letters, Vol. 12, Issue 2, pp. 815-824, (2016) (PubMed).

    Li, Zeng, Qi, Tang, Zhang, Wu, Liang, Shi, Liu, Zhang: "Xenotransplantation of human adipose-derived stem cells in zebrafish embryos." in: PLoS ONE, Vol. 10, Issue 4, pp. e0123264, (2015) (PubMed).

    Wang, Yin, Dong, Zhao, Wang, Wang, Wang, Du, Lu: "Inhibition of Janus kinase-2 signalling pathway ameliorates portal hypertensive syndrome in partial portal hypertensive and liver cirrhosis rats." in: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, Vol. 47, Issue 4, pp. 315-23, (2015) (PubMed).

    Xu, Wang: "Fluid and cell behaviors along a 3D printed alginate/gelatin/fibrin channel." in: Biotechnology and bioengineering, Vol. 112, Issue 8, pp. 1683-95, (2015) (PubMed).

    Xiao, Qiu, Cui, Ni, Li, Liao, Lu, Ding: "MicroRNA-885-3p inhibits the growth of HT-29 colon cancer cell xenografts by disrupting angiogenesis via targeting BMPR1A and blocking BMP/Smad/Id1 signaling." in: Oncogene, Vol. 34, Issue 15, pp. 1968-78, (2015) (PubMed).

    Huan, Wang, Yang, Cui, Wen, Chen, Chen: "Expression and function of the ID1 gene during transforming growth factor-?1-induced differentiation of human embryonic stem cells to endothelial cells." in: Cellular reprogramming, Vol. 17, Issue 1, pp. 59-68, (2015) (PubMed).

    Liu, Wang, Ye, Yin, Chen: "Distinct molecular basis for endothelial differentiation: gene expression profiles of human mesenchymal stem cells versus umbilical vein endothelial cells." in: Cellular immunology, Vol. 289, Issue 1-2, pp. 7-14, (2014) (PubMed).

    Lu, Liu, Zhu, Xu: "Expression of nerve growth factor and hypoxia inducible factor-1? and its correlation with angiogenesis in non-small cell lung cancer." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 3, pp. 359-62, (2014) (PubMed).

    Wang, Jiang, Wang, Li, Zhang, Zhao, Peng, Cao, Sun: "Construction of tissue-engineered bone using a bioreactor and platelet-rich plasma." in: Experimental and therapeutic medicine, Vol. 8, Issue 2, pp. 413-418, (2014) (PubMed).

    Wang, Yang, Wen, Ma, Wang, Yu, Tang, Wu, Dong, Cheng, Nie, Chen: "SKLB-M8 induces apoptosis through the AKT/mTOR signaling pathway in melanoma models and inhibits angiogenesis with decrease of ERK1/2 phosphorylation." in: Journal of pharmacological sciences, Vol. 126, Issue 3, pp. 198-207, (2014) (PubMed).

    Xiu, Fan, Li, Cui, Lei: "Different angiogenic abilities of self-setting calcium phosphate cement scaffolds consisting of different proportions of fibrin glue." in: BioMed research international, Vol. 2014, pp. 785146, (2014) (PubMed).

  • 抗原
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    别名
    PECAM1 (PECAM1 产品)
    别名
    CD31 antibody, CD31/EndoCAM antibody, GPIIA' antibody, PECA1 antibody, PECAM-1 antibody, endoCAM antibody, C85791 antibody, Cd31 antibody, Pecam antibody, platelet/endothelial cell adhesion molecule 1 antibody, platelet and endothelial cell adhesion molecule 1 antibody, pecam1 antibody, PECAM1 antibody, Pecam1 antibody
    背景
    CD31 also known as Platelet endothelial cell adhesion molecule (PECAM-1), is a protein that in human is encoded by the PECAM1 gene. Encoded protein is a member of the immunoglobulin superfamily, CD31 is mapped to 17q23.3. CD31 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. It is demonstrated that CD31 expression on human PBSCs may positively affect both neutrophil and platelet engraftment. Meanwhile, CD31 is involved in leukocyte migration and angiogenesis, which are key components of venous thrombus resolution.

    Synonyms: Adhesion molecule antibody|CD31 antibody|CD31 antigen antibody|CD31 EndoCAM antibody|Endocam antibody|FLJ34100 antibody|FLJ58394 antibody|GPIIA antibody|GPIIA' antibody|PECA1 antibody|PECA1_HUMAN antibody|Pecam 1 antibody|PECAM 1 CD31 EndoCAM antibody|PECAM antibody|PECAM-1 antibody|Pecam1 antibody|Platelet endothelial cell adhesion molecule antibody|Platelet/endothelial cell adhesion molecule 1 antibody|Platelet/endothelial cell adhesion molecule antibody
    基因ID
    5175
    UniProt
    P16284
    途径
    Regulation of Actin Filament Polymerization
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