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CD31 抗体 (AA 681-738)

Name: CD31 抗体 (AA 681-738)
SKU: ABIN726140
Availability: OutOfStock

PECAM1 适用: 人, 小鼠, 大鼠, 兔, Pig, Cow FACS, WB, ELISA, IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated

U937 lysates probed with CD31 Polyclonal Antibody, Unconjugated at 1:300 dilution and 4˚C overnight incubation.

Formalin-fixed and paraffin embedded rabbit sclera tissue labeled with Rabbit Anti-CD31/PECAM-1 Polyclonal Antibody (ABIN726140) at 1:600 followed by conjugation to the secondary antibody and DAB staining.

IHC

3 images

(29 references)

产品编号 ABIN726140

发货至: 中国

Datasheet as PDF

抗原 See all CD31 (PECAM1) 抗体

CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
抗原表位
18

16

15

12

8

8

7

6

5

4

4

4

4

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 681-738
适用
268

128

70

58

40

28

22

17

7

4

4

3

2

1

1

1
人, 小鼠, 大鼠, 兔, Pig, Cow
宿主
151

147

36

7

3

2
兔
Compatible Secondaries
克隆类型
213

132

1
多克隆
标记
149

32

30

23

11

7

7

5

5

5

5

5

5

5

5

5

5

5

4

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1
This CD31 antibody is un-conjugated
应用范围
216

182

95

85

59

36

32

30

25

25

19

15

13

9

6

5

3

3

2

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

交叉反应

Cow, 人, 小鼠, Pig, 兔, 大鼠

预测反应

Dog,Sheep

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human CD31

亚型

IgG

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anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibody
PECAM1 适用: 人, 大鼠 FACS, WB, IHC, IF, StM 宿主: 小鼠 Monoclonal C31-3 unconjugated

anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 625-738) antibody
PECAM1 适用: 人 FACS, IHC, IF, StM 宿主: 小鼠 Monoclonal PECAM1-3527 unconjugated

anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibody
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anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 29-738) antibody
PECAM1 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 1D2-1A5 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Kong, Lee, Youm, Kim, Lee, Suh, Kim: "Effect of treatment with angiopoietin-2 and vascular endothelial growth factor on the quality of xenografted bovine ovarian tissue in mice." in: PLoS ONE, Vol. 12, Issue 9, pp. e0184546, (2018) (PubMed).

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Yang, Pei, Wang, Jin, Yu, Zhou, Zhang, Zhang, Lin: "Tiamulin inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of CD73." in: BMC cancer, Vol. 17, Issue 1, pp. 255, (2017) (PubMed).

Schuerlein, Schwarz, Krziminski, Gätzner, Hoppensack, Schwedhelm, Schweinlin, Walles, Hansmann: "A versatile modular bioreactor platform for Tissue Engineering." in: Biotechnology journal, (2016) (PubMed).

Struecker, Hillebrandt, Raschzok, Jöhrens, Butter, Tang, Andreou, Napierala, Reutzel-Selke, Denecke, Pratschke, Sauer: "Implantation of a Tissue-Engineered Neo-Bile Duct in Domestic Pigs." in: European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes, Vol. 56, Issue 1-2, pp. 61-75, (2016) (PubMed).

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Xiang, Zheng, Zhou, Qiao, Tran, Pu, Li, Kong, Kouzani, Lin, Liu, Li, Shigdar, Duan: "Superior Performance of Aptamer in Tumor Penetration over Antibody: Implication of Aptamer-Based Theranostics in Solid Tumors." in: Theranostics, Vol. 5, Issue 10, pp. 1083-97, (2015) (PubMed).

Karaca, Hulya Uz, Karabacak, Karaboga, Demirtas, Cagatay Cicek: "Effects of hyperthyroidism on expression of vascular endothelial growth factor (VEGF) and apoptosis in fetal adrenal glands." in: European journal of histochemistry : EJH, Vol. 59, Issue 4, pp. 2560, (2015) (PubMed).

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抗原

CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

别名

CD31 (PECAM1 产品)

别名

CD31 antibody, CD31/EndoCAM antibody, GPIIA' antibody, PECA1 antibody, PECAM-1 antibody, endoCAM antibody, C85791 antibody, Cd31 antibody, Pecam antibody, platelet/endothelial cell adhesion molecule 1 antibody, platelet and endothelial cell adhesion molecule 1 antibody, pecam1 antibody, PECAM1 antibody, Pecam1 antibody

背景

Synonyms: CD31, PECA1, GPIIA', PECAM-1, endoCAM, CD31/EndoCAM, Platelet endothelial cell adhesion molecule, PECAM1
Background: Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-69 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Isoform Delta15 is unable to protect against apoptosis. Modulates BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in human umbilical cord vein cells (HUVEC).

基因ID

5175

UniProt

P16284

途径

Regulation of Actin Filament Polymerization