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alpha 2 Macroglobulin 抗体 (C-Term)

This anti-alpha 2 Macroglobulin antibody is a 兔 多克隆 antibody detecting alpha 2 Macroglobulin in IHC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN965491
发货至: 中国

Quick Overview for alpha 2 Macroglobulin 抗体 (C-Term) (ABIN965491)

抗原

See all alpha 2 Macroglobulin (A2M) 抗体
alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

适用

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宿主

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克隆类型

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多克隆

标记

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This alpha 2 Macroglobulin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    纯化方法

    Purified by antigen-specific affinity chromatography.

    免疫原

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human A2M (Alpha-2-macroglobulin precursor)
  • 应用备注

    ELISA, Western blotting: 1µg/ml for 2hrs.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    This antibody is stored in PBS, 50% glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Bishop, Bell: "Assembly of the endoplasmic reticulum phospholipid bilayer: the phosphatidylcholine transporter." in: Cell, Vol. 42, Issue 1, pp. 51-60, (1985) (PubMed).

  • 抗原

    alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

    别名

    A2M

    背景

    A2M(Alpha-2-macroglobulin is able to inhibit all four classes of proteinases by a unique trapping mechanism. This protein has a peptide stretch, called the `bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thiolester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

    途径

    Lipid Metabolism
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