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alpha 2 Macroglobulin 抗体

A2M 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7265558
发货至: 中国
  • 抗原 See all alpha 2 Macroglobulin (A2M) 抗体
    alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
    适用
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    宿主
    • 106
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    克隆类型
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    单克隆
    标记
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    This alpha 2 Macroglobulin antibody is un-conjugated
    应用范围
    • 90
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    原理
    Alpha-2-Macroglobulin (A2M) Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human Alpha-2-Macroglobulin (Alpha-2-Macroglobulin (A2M))
    亚型
    IgG
    Top Product
    Discover our top product A2M Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
    别名
    A2M (A2M 产品)
    别名
    A2MD antibody, CPAMD5 antibody, FWP007 antibody, S863-7 antibody, A2MAC1 antibody, A2m1 antibody, A2maa antibody, Mam antibody, A2mp antibody, A2M antibody, LOC733429 antibody, endod antibody, cpamd5 antibody, fwp007 antibody, s863-7 antibody, a2mb antibody, endodermin antibody, Alpha-2-M antibody, alpha-2-macroglobulin antibody, pregnancy-zone protein L homeolog antibody, alpha-2-macroglobulin S homeolog antibody, pregnancy zone protein antibody, alpha-2-macroglobulin-like antibody, A2M antibody, A2m antibody, LOC477699 antibody, pzp.L antibody, AZL_c00450 antibody, LOC100349077 antibody, a2m antibody, LOC100061656 antibody, LOC100090399 antibody, a2m.S antibody, LOC100469973 antibody, LOC100595735 antibody, PZP antibody, LOC100353095 antibody, LOC101122940 antibody, LOC101801552 antibody, LOC100911545 antibody
    背景
    The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016],A2MD, CPAMD5, FWP007, S863-7,Blood,Blood_Serum Proteins,Cardiovascular,Cell Biology & Developmental Biology,Ubiquitin,A2M
    分子量
    163kDa
    基因ID
    2
    UniProt
    P01023
    途径
    Lipid Metabolism
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