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- 抗原 See all YBX1 抗体
- YBX1 (Y Box Binding Protein 1 (YBX1))
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适用
- Borrelia burgdorferi
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This YBX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Lateral Flow (LF)
- 特异性
- This product was Protein-A purified and cross-adsorbed against MBP from monospecific antiserum by chromatography. This antibody is specific for Borrelia burgdorferi DbpB protein. A BLAST analysis was used to suggest cross-reactivity with DbpB from B. burgdorferi and B. garinii sources based on 100% homology with the immunizing sequence. Cross-reactivity with DbpB from other sources has not been determined.
- 产品特性
- Decorin-binding protein B, or DbpB, binds to decorin, which may mediate the adherence of B.burgdorferi to collagen fibers in skin and other tissues. Spirochetal surface adhesions mediate attachment to decorin, a major component of the host extracellular matrix enabling bacteria to colonize in mammalian tissues. The spirochete migrates from the tick midgut during feeding to its salivary glands and are thus transmitted to the mammal host. This transition may be facilitated by changes in expression of some B. burgdorferi genes. It is believed that expression of the various proteins associated with the spirochete may be regulated by the changes in tick life cycle, changes in conditions during tick feeding (such as temperature, pH, and nutrients) and/or in coordination with the course of infection of the mammal host. Borrelia burgdorferi can colonize multiple tissues, and is capable of attachment to diverse cell types. The expression of decorin-binding protein (Dbp) A and/or DbpB, two B. burgdorferi surface proteins that bind GAGs, is sufficient to convert a high-passage nonadherent B. burgdorferi strain into one that efficiently binds 293 epithelial cells.
- 纯化方法
- purified
- 过滤
- Sterile filtered
- 免疫原
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MBP-fusion protein corresponding to Borrelia burgdorferi Dbp-B protein.
Immunogen Type: RecombinantProtein - 亚型
- IgG
- Top Product
- Discover our top product YBX1 Primary Antibody
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anti-Y Box Binding Protein 1 (YBX1) (AA 100-200) antibody
YBX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) (AA 100-200) antibodyYBX1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) (AA 293-320), (C-Term) antibodyYBX1 适用: 人, 大鼠, 小鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) antibodyYBX1 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) antibodyYBX1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal YBX1-2430 unconjugated
anti-Y Box Binding Protein 1 (YBX1) (AA 51-139) antibodyYBX1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C7 unconjugated
anti-Y Box Binding Protein 1 (YBX1) (N-Term) antibodyYBX1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) antibodyYBX1 适用: 人, 大鼠, 小鼠, Cow, 犬, 小鸡, Pig WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) (pSer102) antibodyYBX1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) antibodyYBX1 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- This protein-A purified antibody has been tested for use in Western blotting. Specific conditions for reactivity should be optimized by the user. Expect a band approximately 17.9 kDa in size corresponding to Borrelia burgdorferi DbpB protein by Western blotting in the appropriate cell lysate or extract.
- 说明
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Gene Name: dbpB, BB_A25
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
- 浓度
- 1.0 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
- 有效期
- 12 months
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- 抗原
- YBX1 (Y Box Binding Protein 1 (YBX1))
- 别名
- DbpB (YBX1 产品)
- 别名
- BP-8 antibody, CSDA2 antibody, CSDB antibody, DBPB antibody, MDR-NF1 antibody, NSEP-1 antibody, NSEP1 antibody, YB-1 antibody, YB1 antibody, Byb1 antibody, Cbfa antibody, Dbpb antibody, Ef1a antibody, Msy1 antibody, Nsep1 antibody, Yb1 antibody, bp-8 antibody, csda2 antibody, csdb antibody, dbpb antibody, frgy1 antibody, mdr-nf1 antibody, nsep-1 antibody, nsep1 antibody, yb1 antibody, 1700102N10Rik antibody, C79409 antibody, EF1A antibody, MSY1 antibody, dbpB antibody, mYB-1a antibody, nuclease sensitive element binding protein 1 antibody, Y-box binding protein 1 antibody, Y box binding protein 1 antibody, Y-box binding protein 1 S homeolog antibody, nuclease-sensitive element-binding protein 1 antibody, Y box protein 1 antibody, nsep1 antibody, YBX1 antibody, Ybx1 antibody, ybx1.S antibody, LOC479011 antibody
- 背景
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Decorin-binding protein B, or DbpB, binds to decorin, which may mediate the adherence of B.burgdorferi to collagen fibers in skin and other tissues. Spirochetal surface adhesions mediate attachment to decorin, a major component of the host extracellular matrix enabling bacteria to colonize in mammalian tissues. The spirochete migrates from the tick midgut during feeding to its salivary glands and are thus transmitted to the mammal host. This transition may be facilitated by changes in expression of some B. burgdorferi genes. It is believed that expression of the various proteins associated with the spirochete may be regulated by the changes in tick life cycle, changes in conditions during tick feeding (such as temperature, pH, and nutrients) and/or in coordination with the course of infection of the mammal host. Borrelia burgdorferi can colonize multiple tissues, and is capable of attachment to diverse cell types. The expression of decorin-binding protein (Dbp) A and/or DbpB, two B. burgdorferi surface proteins that bind GAGs, is sufficient to convert a high-passage nonadherent B. burgdorferi strain into one that efficiently binds 293 epithelial cells.
Synonyms: Decorin-binding protein B, Borrelia burgdorferi DbpB - 基因ID
- 1194341
- NCBI登录号
- NP_045698
- UniProt
- O50918
- 途径
- Regulation of Muscle Cell Differentiation
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