PYM 抗体 (N-Term)
Quick Overview for PYM 抗体 (N-Term) (ABIN955577)
抗原
See all PYM (WIBG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-44, N-Term
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特异性
- This antibody detects WIBG / PYM (N-term).
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse
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纯化方法
- Protein A column followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human WIBG
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亚型
- Ig Fraction
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anti-Partner of Y14 and mago (WIBG) (AA 81-130) antibody
WIBG 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Partner of Y14 and mago (WIBG) (C-Term) antibodyWIBG 适用: 人, Cow, 犬, 马, Pig, Bat, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Partner of Y14 and mago (WIBG) antibodyWIBG 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Partner of Y14 and mago (WIBG) (AA 12-40), (N-Term) antibodyWIBG 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB28144 unconjugated
anti-Partner of Y14 and mago (WIBG) (C-Term) antibodyWIBG 适用: 人, 小鼠, Cow, 犬, 马, 豚鼠, 兔, 大鼠, Saccharomyces cerevisiae, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- PYM (WIBG) (Partner of Y14 and mago (WIBG))
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别名
- WIBG / PYM
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背景
- Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions. May bind RNA, the relevance of RNA-binding remains unclear in vivo, RNA-binding was detected by PubMed:14968132, while PubMed:19410547 did not detect RNA-binding activity independently of the EJC.Synonyms: Partner of Y14 and mago, Protein wibg homolog
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基因ID
- 84305
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NCBI登录号
- NP_001137325
抗原
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