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PYM 抗体 (C-Term)

WIBG 适用: 人, 小鼠, Cow, 犬, 马, 豚鼠, 兔, 大鼠, Saccharomyces cerevisiae, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2788485
发货至: 中国
  • 抗原 See all PYM (WIBG) 抗体
    PYM (WIBG) (Partner of Y14 and mago (WIBG))
    抗原表位
    • 8
    • 8
    • 7
    • 1
    • 1
    • 1
    C-Term
    适用
    • 29
    • 18
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, Cow, 犬, 马, 豚鼠, 兔, 大鼠, Saccharomyces cerevisiae, Pig
    宿主
    • 27
    • 2
    克隆类型
    • 27
    • 2
    多克隆
    标记
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PYM antibody is un-conjugated
    应用范围
    • 21
    • 15
    • 13
    • 5
    • 1
    • 1
    Western Blotting (WB)
    序列
    KKIKNLKKKL RQVEELQQRI QAGEVSQPSK EQLEKLARRR ALEEELEDLE
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%, Yeast: 100%
    产品特性
    This is a rabbit polyclonal antibody against WIBG. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human WIBG
    Top Product
    Discover our top product WIBG Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 204 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PYM (WIBG) (Partner of Y14 and mago (WIBG))
    别名
    WIBG (WIBG 产品)
    别名
    BEST:HL05757 antibody, CG10330 antibody, CG30176 antibody, Dmel\\CG30176 antibody, PYM antibody, Pym antibody, UD3 antibody, A030010B05Rik antibody, zgc:65891 antibody, zgc:77281 antibody, Partner of Y14 and Mago antibody, Wibg protein antibody, PYM homolog 1, exon junction complex associated factor L homeolog antibody, PYM homolog 1, exon junction complex associated factor antibody, Pym antibody, wibg antibody, pym1.L antibody, PYM1 antibody, Pym1 antibody, pym1 antibody
    背景
    WIBG is a key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. It acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. It interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions.
    Alias Symbols: MGC13064, PYM
    Protein Interaction Partner: RTN4IP1, UBC, RPS19, RPS14, RPS13, RPS12, RPS10, RPS9, RPS8, RPS7, RPS6, RPS5, RPS4X, RPS3A, RPS3, RPS2, FAU, BYSL, ZNF503, PNO1, KCMF1, TSR1, RPS27L, UBQLN1, RPS29, RPS28, RPS27, RPS26, RPS25, RPS24, RPS23, RPS20, RPS18, RPS16, RPS15A, TARDBP, MAGOH, TOE
    Protein Size: 204
    分子量
    23 kDa
    基因ID
    84305
    NCBI登录号
    NM_032345, NP_115721
    UniProt
    Q9BRP8
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