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PYM 抗体

WIBG 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7269181
发货至: 中国
  • 抗原 See all PYM (WIBG) 抗体
    PYM (WIBG) (Partner of Y14 and mago (WIBG))
    适用
    • 30
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 28
    • 2
    克隆类型
    • 28
    • 2
    多克隆
    标记
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PYM antibody is un-conjugated
    应用范围
    • 22
    • 15
    • 13
    • 6
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    原理
    PYM1 Rabbit pAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human PYM1.
    亚型
    IgG
    Top Product
    Discover our top product WIBG Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PYM (WIBG) (Partner of Y14 and mago (WIBG))
    别名
    PYM1 (WIBG 产品)
    别名
    BEST:HL05757 antibody, CG10330 antibody, CG30176 antibody, Dmel\\CG30176 antibody, PYM antibody, Pym antibody, UD3 antibody, A030010B05Rik antibody, zgc:65891 antibody, zgc:77281 antibody, Partner of Y14 and Mago antibody, Wibg protein antibody, PYM homolog 1, exon junction complex associated factor L homeolog antibody, PYM homolog 1, exon junction complex associated factor antibody, Pym antibody, wibg antibody, pym1.L antibody, PYM1 antibody, Pym1 antibody, pym1 antibody
    背景
    Key regulator of the exon junction complex (EJC, a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD or translation. Acts as an EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions. May bind RNA, the relevance of RNA-binding remains unclear in vivo, RNA-binding was detected by PubMed:14968132, while PubMed:19410547 did not detect RNA-binding activity independently of the EJC.,PYM, WIBG,Epigenetics & Nuclear Signaling,PYM1
    基因ID
    84305
    UniProt
    Q9BRP8
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