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SSRP1 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects SSRP1 in WB 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN954958
发货至: 中国
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Quick Overview for SSRP1 抗体 (C-Term) (ABIN954958)

抗原

See all SSRP1 抗体
SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

适用

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宿主

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克隆类型

  • 53
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多克隆

标记

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This SSRP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 489-518, C-Term

    特异性

    This antibody recognizes Human SSRP1 / FACT80 (C-term).

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 489-518 amino acids from the C-terminal region of Human SSRP1. Genename: SSRP1

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

    别名

    SSRP1 / FACT80

    背景

    The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.Synonyms: Chromatin-specific transcription elongation factor 80 kDa subunit, FACT 80 kDa subunit, FACT complex subunit SSRP1, FACTp80, Facilitates chromatin transcription complex subunit SSRP1, Recombination signal sequence recognition protein 1, Structure-specific recognition protein 1, T160

    分子量

    81075 Da

    基因ID

    6749

    NCBI登录号

    NP_003137

    途径

    Chromatin Binding
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