Septin 2 抗体 (C-Term)
Quick Overview for Septin 2 抗体 (C-Term) (ABIN954726)
抗原
See all Septin 2 (SEPT2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 279-309, C-Term
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特异性
- Recognizes SEPT2 (C-term).
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纯化方法
- Protein A column followed by peptide Affinity purification
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免疫原
- KLH conjugated synthetic peptide between 279-309 amino acids from the C-terminal region of Human SEPT2 Genename: SEPT2
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Septin 2 (SEPT2)
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别名
- Septin-2
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背景
- Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.Synonyms: DIFF6, KIAA0158, NEDD-5, NEDD5, Neural precursor cell expressed developmentally down-regulated protein 5, SEPT-2, SEPT2, Septin2
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基因ID
- 4735
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NCBI登录号
- NP_001008491
抗原
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