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S100A8 抗体 (Biotin)

This anti-S100A8 antibody is a 小鼠 单克隆 antibody detecting S100A8 in WB, IF, FACS 和 IHC (p). Suitable for 人.
产品编号 ABIN954652
发货至: 中国

Quick Overview for S100A8 抗体 (Biotin) (ABIN954652)

抗原

See all S100A8 抗体
S100A8 (S100 Calcium Binding Protein A8 (S100A8))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This S100A8 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

CF-145
  • 特异性

    This antibody detects Calgranulin A (S100A8).

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Protein G Chromatography of Ascitic fluid.

    免疫原

    Purified granulocyte antigen of Human origin.

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    S100A8 (S100 Calcium Binding Protein A8 (S100A8))

    别名

    S100A8 / Calgranulin-A / MRP8

    背景

    Calgranulin A, also known as MRP-8 and S100A8 is a member of the S100 family of proteins containing 2 EF hand (alpha helix, turn, alpha helix structure) calcium binding motifs. S100 proteins are localized in the cytoplasm and /or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. MRP-8 (S100A8) forms a heterodimeric complex with Calgranulin B, (MRP-14, S100A9) in the cytosol of monocyte and neutrophil cell types circulating in peripheral blood. Calgranulin A is found in elevated levels in the serum of cystic fibrosis cases and is also expressed in the skin of patients with psoriasis, eczematous dermatitis and squamous cell carcinoma.Synonyms: CAGA, CFAG, Calprotectin L1L subunit, Cystic fibrosis antigen, Leukocyte L1 complex light chain, MRP-8, Migration inhibitory factor-related protein 8, S100 calcium-binding protein A8, S100-A8, Urinary stone protein band A

    基因ID

    6279

    NCBI登录号

    NP_002955

    UniProt

    P05109

    途径

    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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