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C10orf2 抗体 (C-Term)

This anti-C10orf2 antibody is a 兔 多克隆 antibody detecting C10orf2 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN954086
发货至: 中国

Quick Overview for C10orf2 抗体 (C-Term) (ABIN954086)

抗原

See all C10orf2 (C10ORF2) 抗体
C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

适用

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宿主

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克隆类型

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多克隆

标记

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This C10orf2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 663-684, C-Term

    特异性

    This antibody reacts to PEO1.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 663-684 amino acids from the C-terminal region of human C10orf2

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) sodium azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

    别名

    PEO1 / Twinkle

    背景

    This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.Synonyms: C10orf2, Progressive external ophthalmoplegia 1 protein, T7-like mitochondrial DNA helicase, Twinkle protein mitochondrial

    基因ID

    56652

    NCBI登录号

    NP_001157284
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