PARP2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.Synonyms: ADPRT2, ADPRTL2, EC=2.4.2.30, NAD(+) ADP-ribosyltransferase 2, PARP 2, PARP-2, Poly [ADP-ribose] polymerase 2, Poly[ADP-ribose] synthetase 2, pADPRT-2