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PARP2 抗体 (Internal Region)

PARP2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259061
发货至: 中国
  • 抗原 See all PARP2 抗体
    PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))
    抗原表位
    • 8
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 43
    • 37
    • 11
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    人, 小鼠
    宿主
    • 57
    • 1
    • 1
    克隆类型
    • 49
    • 10
    多克隆
    标记
    • 27
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This PARP2 antibody is un-conjugated
    应用范围
    • 36
    • 22
    • 7
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    PARP2 Antibody detects endogenous levels of total PARP2.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human PARP2, corresponding to a region within the internal amino acids.
    亚型
    IgG
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))
    别名
    PARP2 (PARP2 产品)
    别名
    ADPRT2 antibody, ADPRTL2 antibody, ADPRTL3 antibody, ARTD2 antibody, PARP-2 antibody, pADPRT-2 antibody, Adprt2 antibody, Adprtl2 antibody, Aspartl2 antibody, C78626 antibody, cb996 antibody, adprtl2 antibody, ADPRT-2 antibody, APP antibody, ATPARP1 antibody, PARP1 antibody, POLY(ADP-RIBOSE) POLYMERASE antibody, POLY(ADP-RIBOSE) POLYMERASE 1 antibody, PP antibody, T14P8.19 antibody, T14P8_19 antibody, poly(ADP-ribose) polymerase antibody, poly(ADP-ribose) polymerase 2 antibody, poly(ADP-ribose) polymerase 2 antibody, poly (ADP-ribose) polymerase family, member 2 antibody, poly (ADP-ribose) polymerase 2 antibody, poly(ADP-ribose) polymerase 2 S homeolog antibody, poly(ADP-ribose) polymerase antibody, PARP2 antibody, Parp2 antibody, parp2 antibody, parp2.S antibody
    背景

    Description: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism (PubMed:10364231, PubMed:28190768). This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (PubMed:10364231). Mediates serine ADP-ribosylation of target proteins following interaction with HPF1, HPF1 conferring serine specificity (PubMed:28190768).

    Gene: PARP2

    分子量
    75 kDa
    基因ID
    10038
    UniProt
    Q9UGN5
    途径
    DNA Damage Repair
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