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PABPN1 抗体 (C-Term)

This anti-PABPN1 antibody is a 兔 多克隆 antibody detecting PABPN1 in WB 和 EIA. Suitable for 人.
产品编号 ABIN953974
发货至: 中国

Quick Overview for PABPN1 抗体 (C-Term) (ABIN953974)

抗原

See all PABPN1 抗体
PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))

适用

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宿主

  • 30

克隆类型

  • 18
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多克隆

标记

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This PABPN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 8
    • 2
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    AA 269-298, C-Term

    特异性

    This antibody recognizes Human PABPN1 (C-term).

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 269-298 amino acids from the C-terminal region of human PABPN1

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))

    别名

    PABPN1

    背景

    This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails on the 3' ends of eukaryotic genes and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. An expansion of the trinucleotide (GCG) repeat from normal 6 to 8-13 at the 5' end of the coding region of this gene leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Multiple splice variants have been described but their full-length nature is not known. One splice variant includes introns 1 and 6 but no protein is formed.Synonyms: Nuclear poly(A)-binding protein 1, PAB2, PABP-2, PABP2, Poly(A)-binding protein 2, Polyadenylate-binding nuclear protein 1, Polyadenylate-binding protein 2

    分子量

    32749 Da

    基因ID

    8106

    NCBI登录号

    NP_004634
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