PABPN1 抗体 (C-Term)
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Quick Overview for PABPN1 抗体 (C-Term) (ABIN953974)
抗原
See all PABPN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 269-298, C-Term
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特异性
- This antibody recognizes Human PABPN1 (C-term).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 269-298 amino acids from the C-terminal region of human PABPN1
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
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别名
- PABPN1
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背景
- This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails on the 3' ends of eukaryotic genes and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. An expansion of the trinucleotide (GCG) repeat from normal 6 to 8-13 at the 5' end of the coding region of this gene leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Multiple splice variants have been described but their full-length nature is not known. One splice variant includes introns 1 and 6 but no protein is formed.Synonyms: Nuclear poly(A)-binding protein 1, PAB2, PABP-2, PABP2, Poly(A)-binding protein 2, Polyadenylate-binding nuclear protein 1, Polyadenylate-binding protein 2
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分子量
- 32749 Da
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基因ID
- 8106
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NCBI登录号
- NP_004634
抗原
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