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PABPN1 抗体 (C-Term)

PABPN1 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN953974
发货至: 中国
  • 抗原 See all PABPN1 抗体
    PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
    抗原表位
    • 8
    • 2
    • 2
    • 2
    • 2
    • 1
    AA 269-298, C-Term
    适用
    • 28
    • 13
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    宿主
    • 28
    克隆类型
    • 18
    • 10
    多克隆
    标记
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PABPN1 antibody is un-conjugated
    应用范围
    • 20
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes Human PABPN1 (C-term).
    纯化方法
    Protein A column, followed by peptide affinity purification
    免疫原
    KLH conjugated synthetic peptide between 269-298 amino acids from the C-terminal region of human PABPN1
    亚型
    Ig Fraction
    Top Product
    Discover our top product PABPN1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
    别名
    PABPN1 (PABPN1 产品)
    背景
    This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails on the 3' ends of eukaryotic genes and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. An expansion of the trinucleotide (GCG) repeat from normal 6 to 8-13 at the 5' end of the coding region of this gene leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Multiple splice variants have been described but their full-length nature is not known. One splice variant includes introns 1 and 6 but no protein is formed.Synonyms: Nuclear poly(A)-binding protein 1, PAB2, PABP-2, PABP2, Poly(A)-binding protein 2, Polyadenylate-binding nuclear protein 1, Polyadenylate-binding protein 2
    分子量
    32749 Da
    基因ID
    8106
    NCBI登录号
    NP_004634
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