NEDD4-2 抗体 (Middle Region)
Quick Overview for NEDD4-2 抗体 (Middle Region) (ABIN953641)
抗原
See all NEDD4-2 (NEDD4L) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 575-604, Middle Region
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特异性
- This antibody recognizes Human and Mouse NEDD4L (Center).
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纯化方法
- Protein A column, followed by peptide affinity purification
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免疫原
- KLH conjugated synthetic peptide between 575-604 amino acids from the Central region of human NEDD4L
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亚型
- Ig Fraction
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anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 1-100) antibody
NEDD4L 适用: 人 ELISA, WB, IP 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 836-955) antibodyNEDD4L 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) antibodyNEDD4L 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 289-494) antibodyNEDD4L 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) antibodyNEDD4L 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (pSer448) antibodyNEDD4L 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (Middle Region) antibodyNEDD4L 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 1-100) antibodyNEDD4L 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 275-325) antibodyNEDD4L 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig WB, IHC, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 225-275) antibodyNEDD4L 适用: 人, 小鼠, Cow, Pig, 兔 WB, IHC, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- NEDD4-2 (NEDD4L) (E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
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别名
- NEDD4L
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背景
- E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK.Synonyms: KIAA0439, NEDD4.2, NEDL3, Nedd4-2
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分子量
- 111932 Da
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基因ID
- 23327
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NCBI登录号
- NP_001138436
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途径
- Negative Regulation of Transporter Activity
抗原
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