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NEDD4-2 抗体

NEDD4L 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7266882
发货至: 中国
  • 抗原 See all NEDD4-2 (NEDD4L) 抗体
    NEDD4-2 (NEDD4L) (E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
    适用
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    宿主
    • 76
    • 4
    克隆类型
    • 70
    • 10
    单克隆
    标记
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    This NEDD4-2 antibody is un-conjugated
    应用范围
    • 37
    • 25
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    Western Blotting (WB)
    原理
    NEDD4L Rabbit mAb
    交叉反应
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human NEDD4L
    亚型
    IgG
    Top Product
    Discover our top product NEDD4L Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    NEDD4-2 (NEDD4L) (E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
    别名
    NEDD4L (NEDD4L 产品)
    别名
    NEDD4-2 antibody, NEDD4.2 antibody, RSP5 antibody, hNEDD4-2 antibody, nedd4 antibody, nedd4-2 antibody, NEDD4 antibody, Nedd4-2 antibody, 1300012C07Rik antibody, Nedd4b antibody, neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase antibody, NEDD4L antibody, neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase S homeolog antibody, neural precursor cell expressed, developmentally down-regulated gene 4-like antibody, NEDD4L antibody, LOC776799 antibody, nedd4l.S antibody, Nedd4l antibody
    背景
    This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012],NEDD4-2, NEDD4.2, PVNH7, RSP5, hNEDD4-2,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Protein phosphorylation,Ubiquitin,Ubiquitin_Ubiquitin-Proteasome Signaling Pathway,NEDD4L
    分子量
    130kDa
    基因ID
    23327
    UniProt
    Q96PU5
    途径
    Negative Regulation of Transporter Activity
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