MUTYH 抗体 (Middle Region)
Quick Overview for MUTYH 抗体 (Middle Region) (ABIN953552)
抗原
See all MUTYH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 352-381, Middle Region
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特异性
- This antibody recognizes MUTYH.
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse
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纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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免疫原
- Synthetic peptide - KLH conjugated - corresponding to the central region (between 352-381aa) of human MUTYH.
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MUTYH (MutY Homolog (E. Coli) (MUTYH))
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别名
- MUTYH
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背景
- MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair and initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.Synonyms: A/G-specific adenine DNA glycosylase, MYH, MutY homolog
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基因ID
- 4595
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NCBI登录号
- NP_001041636
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途径
- DNA Damage Repair
抗原
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