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MED14 抗体 (Middle Region)

This anti-MED14 antibody is a 兔 多克隆 antibody detecting MED14 in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN953367
发货至: 中国

Quick Overview for MED14 抗体 (Middle Region) (ABIN953367)

抗原

See all MED14 抗体
MED14 (Mediator Complex Subunit 14 (MED14))

适用

  • 24
  • 16
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 27
  • 3

克隆类型

  • 27
  • 3
多克隆

标记

  • 18
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MED14 antibody is un-conjugated

应用范围

  • 18
  • 14
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 585-615, Middle Region

    特异性

    This antibody recognizes Human and Mouse MED14 (Center).

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    KLH conjugated synthetic peptide between 585-615 amino acids from the Central region of human MED14

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MED14 (Mediator Complex Subunit 14 (MED14))

    别名

    MED14

    背景

    The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.Synonyms: ARC150, Activator-recruited cofactor 150 kDa component, CRSP complex subunit 2, CRSP2, CXorf4, Cofactor required for Sp1 transcriptional activation subunit 2, DRIP150, EXLM1, Mediator of RNA polymerase II transcription subunit 14, RGR1, TRAP170 Mediator complex 14, Thyroid hormone receptor-associated protein complex 170 kDa component, Transcriptional coactivator CRSP150, Vitamin D3 receptor-interacting protein complex 150 kDa component

    分子量

    160607 Da

    基因ID

    9282

    NCBI登录号

    NP_004220

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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