MED14 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for MED14 抗体 (Middle Region) (ABIN2787568)
抗原
See all MED14 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
原理
- MED14 Antibody - middle region
-
序列
- AADREDSPAM ALLLQQFKEN IQDLVFRTKT GKQTRTNAKR KLSDDPCPVE
-
预测反应
- Human: 100%, Mouse: 79%, Rabbit: 86%
-
产品特性
- This is a rabbit polyclonal antibody against MED14. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MED14
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58139-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- MED14 (Mediator Complex Subunit 14 (MED14))
-
别名
- MED14
-
背景
-
Targeted Subunit: 14
Background Information: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.
Gene Name: Mediator complex subunit 14
Alternative Symbols: CSRP, RGR1, CRSP2, EXLM1, CXorf4, CRSP150, DRIP150, TRAP170
Protein Name: Mediator of RNA polymerase II transcription subunit 14
-
分子量
- 161 kDa
-
基因ID
- 9282
-
NCBI登录号
- NP_004220
-
UniProt
- O60244
-
途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
抗原
-