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MED14 抗体 (AA 701-750)

The 兔 多克隆 anti-MED14 antibody (ABIN1533515) specifically detects MED14 in ELISA, IHC 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1533515
发货至: 中国
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Quick Overview for MED14 抗体 (AA 701-750) (ABIN1533515)

抗原

See all MED14 抗体
MED14 (Mediator Complex Subunit 14 (MED14))

适用

  • 36
  • 28
  • 12
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 39
  • 3
兔

克隆类型

  • 39
  • 3
多克隆

标记

  • 20
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MED14 antibody is un-conjugated

应用范围

  • 31
  • 23
  • 7
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 12
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 701-750

    原理

    CRSP150 Antibody

    特异性

    CRSP150 Polyclonal Antibody detects endogenous levels of CRSP150 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human MED14. AA range:701-750

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MED14 (Mediator Complex Subunit 14 (MED14))

    别名

    MED14

    背景

    Synonyms: MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170, Mediator of RNA polymerase II transcription subunit 14, Activator-recruited cofactor 150 kDa component, ARC150, Cofactor required for Sp1 transcriptional activation subunit 2, CRS

    Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus.The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. [provided by RefSeq, Jul 2008],

    Gene Name: MED14

    Protein Name: Mediator of RNA polymerase II transcription subunit 14

    分子量

    160 kDa

    基因ID

    9282

    OMIM

    300182

    UniProt

    O60244

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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