INHBA 抗体 (N-Term)
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Quick Overview for INHBA 抗体 (N-Term) (ABIN952902)
抗原
See all INHBA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 92-119, N-Term
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特异性
- This antibody reacts to INHBA.
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交叉反应 (详细)
- Species reactivity (expected):Mouse, Rat, BovineSpecies reactivity (tested):Human.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- This INHBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-119 amino acids from the N-terminal region of human INHBA.
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -80 °C for longer.
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- INHBA (Inhibin, beta A (INHBA))
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别名
- Inhibin beta A Chain (INHBA)
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背景
- The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.Synonyms: Activin A, Activin BA, Activin beta-A chain, Erythroid differentiation protein
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分子量
- 47442 Da
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基因ID
- 3624
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NCBI登录号
- NP_002183
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途径
- Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagy
抗原
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