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INHBA 抗体 (C-Term)

KO Validated INHBA 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856600
发货至: 中国
  • 抗原 See all INHBA 抗体
    INHBA (Inhibin, beta A (INHBA))
    抗原表位
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 59
    • 30
    • 25
    • 10
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 79
    • 11
    克隆类型
    • 79
    • 12
    多克隆
    标记
    • 49
    • 16
    • 11
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This INHBA antibody is un-conjugated
    应用范围
    • 79
    • 44
    • 34
    • 21
    • 20
    • 14
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    产品特性
    Rabbit Polyclonal antibody to Inhibin beta A (inhibin, beta A)
    Inhibin beta A antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Inhibin beta A. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product INHBA Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.66 mg/mL
    缓冲液
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    INHBA (Inhibin, beta A (INHBA))
    别名
    inhibin subunit beta A (INHBA 产品)
    别名
    EDF antibody, FRP antibody, actba antibody, inhba antibody, inhbaa-001 antibody, edf antibody, frp antibody, INHB antibody, inhbal antibody, zgc:158348 antibody, inhibin beta A subunit antibody, inhibin beta-A antibody, inhibin, beta Aa antibody, inhibin beta A antibody, inhibin, beta Ab antibody, INHBA antibody, Inhba antibody, inhbaa antibody, inhba antibody, inhbab antibody
    背景
    The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

    Cellular Localization: Secreted
    分子量
    47 kDa
    基因ID
    3624
    UniProt
    P08476
    途径
    Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagy
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