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FGFRL1 抗体 (N-Term)

This anti-FGFRL1 antibody is a 兔 多克隆 antibody detecting FGFRL1 in WB 和 EIA. Suitable for 人.
产品编号 ABIN952316
发货至: 中国

Quick Overview for FGFRL1 抗体 (N-Term) (ABIN952316)

抗原

See all FGFRL1 抗体
FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

适用

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宿主

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克隆类型

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多克隆

标记

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This FGFRL1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody reacts to FGFRL1.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography on Protein A

    免疫原

    The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS, 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

    别名

    FGFRL1

    背景

    Synonyms: FGF homologous factor receptor, FGFR-like protein, FGFR5, FHFR, Fibroblast growth factor receptor 5, Fibroblast growth factor receptor-like 1

    分子量

    54537 Da

    基因ID

    53834

    NCBI登录号

    NP_001004356

    途径

    RTK signaling
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