COPS7A 抗体 (C-Term)
Quick Overview for COPS7A 抗体 (C-Term) (ABIN951662)
抗原
See all COPS7A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 244-274, C-Term
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特异性
- This antibody reacts to COPS7A.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide between 244-274 amino acids from the C-terminal region of human COPS7A
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亚型
- Ig Fraction
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anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (AA 1-275) antibody
COPS7A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (AA 2-275) antibodyCOPS7A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (AA 1-275) antibodyCOPS7A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (C-Term) antibodyCOPS7A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (C-Term) antibodyCOPS7A 适用: 人, 小鼠, 大鼠, 猴, Cow, 犬, 豚鼠, 马, 兔, Bat, 小鸡, Hamster, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (AA 237-266), (C-Term) antibodyCOPS7A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32335 unconjugated
anti-COP9 Signalosome Complex Subunit 7a (COPS7A) (Middle Region) antibodyCOPS7A 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
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别名
- COPS7A
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背景
- Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.Synonyms: COP9 signalosome complex subunit 7a, CSN7A, DERP10, Dermal papilla-derived protein 10, JAB1-containing signalosome subunit 7a, SGN7a, Signalosome subunit 7a
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分子量
- 30277 Da
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基因ID
- 50813
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NCBI登录号
- NP_001157565
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途径
- Cell Division Cycle
抗原
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