CD73 抗体
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- 抗原 See all CD73 (NT5E) 抗体
- CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD73 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody recognizes CD73, a 70 kDa GPI-anchored 5´-nucleotidase expressed predominantly on T and B cell subsets, follicular dendritic cells and endothelial cells.
- 交叉反应 (详细)
- Species reactivity (tested):Human
- 纯化方法
- Protein A affinity chromatography
- 克隆位点
- AD2
- 亚型
- IgG1
- Top Product
- Discover our top product NT5E Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
- 别名
- CD73 (NT5E 产品)
- 背景
- CD73 (ecto-5´-nucleotidase) is a 70 kDa glycoprotein anchored to the extracellular leaflet of the plasma membrane by GPI. This ecto-enzyme catalyzes dephosphorylation of AMP to adenosine. CD73 is expressed in various types of cells, such as epithelial, muscle, and endothelial cells, neutrophils, lymphocytes and fibroblasts. Inflammatory mediators support CD73 expression and its enzymatic activity, leading to the release of adenosine, which modulates inflammation through adenosine receptors. CD73 is expressed in a variety of lymphomas and leukemias, including ALL and CLL, whereas immunodeficient patients usually express low levels of this protein.Synonyms: 5'-nucleotidase, NT5, NT5E, NTE
- 基因ID
- 4907
- NCBI登录号
- NP_001191742
- UniProt
- P21589
- 途径
- Synaptic Membrane, Ribonucleoside Biosynthetic Process
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